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A ‘living bandage’ made from stem cells, which could revolutionise the treatment and prognosis of a common sporting knee injury, has been trialled in humans for the first time by scientists at the Universities of Liverpool and Bristol.

Meniscal tears are suffered by over one million people a year in the US and Europe alone and are particularly common in contact sports like football and rugby. 90% or more of tears occur in the white zone of meniscus which lacks a blood supply, making them difficult to repair. Many professional sports players opt to have the torn tissue removed altogether, risking osteoarthritis in later life.

The Cell Bandage has been developed by spin-out company Azellon, and is designed to enable the meniscal tear to repair itself by encouraging cell growth in the affected tissue.

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Earlier this year, after 100 years of searching for them, an international team of researchers detected the presence of gravitational waves for the first time, thanks to the collision of two massive black holes, providing proof for Einstein’s general theory of relativity.

Needless to say, it was a big deal, but two important questions remained: where did the two colliding black holes that created these gravitational ripples in space-time come from, and how did they get so massive?

Black holes form when a star runs out of fuel and collapses in on itself.

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As pubs and bars in the UK get busier in the run up to Christmas, Barclaycard has uncorked a way to reduce the time people spend waiting to be served. Pay @ Pump is a beer pump that allows customers to pour their own pint and pay with a contactless card in as little as a minute.

According to Barclaycard, people spend an average of 12 minutes per order waiting to be served over the Christmas period. The Pay @ Pump system is designed to reduce customer queuing time and speed up service.

“I’m sure everyone has been stuck behind the person who orders the most complicated cocktail on the menu or a round of 10 drinks for their group of friends,” explains Barclaycard’s commercial director for digital consumer payments Tami Hargreaves. “When people told us that waiting time was one of their biggest annoyances, we wanted to help solve a common problem with a simple solution.”

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My new story for New Scientist on robot voting rights. This story came about because of my discussion with Professor Lawrence Lessig on the BBC World Service. To read my article, you may have to sign up for a free New Scientist account (it takes 1 minute). Please do it! It’s an important article. Gerrymandering in the AI and & robot age: https://www.newscientist.com/article/mg23231043-300-prep…ith-votes/ #transhumanism

If human-like AI comes to fruition then we may have grant voting rights to our silicon equals. Democracy will change forever, says Zoltan Istvan.

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Check out the LEAF interview with Synthetic Biology company CellAge who plan to use their technology to create aging biomarkers for the research community to use for free as well as new approaches to removing senescent cells.

CellAge are using synthetic biology to remove senescent cells that accumulate with age and contribute to disease. We took the time to interview them about their technology, treating age-related diseases and their plans for the future.

You can also check out their campaign on Lifespan.io:

https://www.lifespan.io/campaigns/cellage-targeting-senescen…c-biology/

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Progress with treating osteoporosis.

A team of scientists at the Children’s Medical Center Research Institute at UT Southwestern (CRI) discovered a new bone-forming growth factor, Osteolectin (Clec11a), which reverses osteoporosis in mice and has implications for regenerative medicine.

Although Osteolectin is known to be made by certain marrow and , CRI researchers are the first to show Osteolectin promotes the formation of new bone from skeletal stem cells in the bone marrow. The study, published in eLife, also found that deletion of Osteolectin in mice causes accelerated bone loss during adulthood and symptoms of , such as reduced bone strength and delayed fracture healing.

“These results demonstrate the important role Osteolectin plays in new bone formation and maintaining adult bone mass. This study opens up the possibility of using this growth factor to treat diseases like osteoporosis,” said Dr. Sean Morrison, who led the team that made the discovery. Dr. Morrison, CRI Director, holds the Mary McDermott Cook Chair in Pediatric Genetics at UT Southwestern Medical Center, and the Kathryne and Gene Bishop Distinguished Chair in Pediatric Research at Children’s Research Institute at UT Southwestern.

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