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Oct 8, 2012

Stanford Bioengineers Introduce ‘Bi-Fi’ — The Biological Internet

Posted by in categories: biotech/medical, chemistry

Using an innocuous bacterial virus, bioengineers have created a biological mechanism to send genetic messages from cell to cell. The system greatly increases the complexity and amount of data that can be communicated between cells and could lead to greater control of biological functions within cell communities…

In harnessing DNA for cell-cell messaging the researchers have also greatly increased the amount of data they can transmit at any one time. In digital terms, they have increased the bit rate of their system. The largest DNA strand M13 is known to have packaged includes more than 40,000 base pairs. Base pairs, like 1s and 0s in digital encoding, are the basic building blocks of genetic data. Most genetic messages of interest in bioengineering range from several hundred to many thousand base pairs.

Ortiz was even able to broadcast her genetic messages between cells separated by a gelatinous medium at a distance of greater than 7 centimeters.

“That’s very long-range communication, cellularly speaking,” she said.

Down the road, the biological Internet could lead to biosynthetic factories in which huge masses of microbes collaborate to make more complicated fuels, pharmaceuticals and other useful chemicals. With improvements, the engineers say, their cell-cell communication platform might someday allow more complex three-dimensional programming of cellular systems, including the regeneration of tissue or organs.

Continue reading “Stanford Bioengineers Introduce ‘Bi-Fi’ — The Biological Internet”

Oct 8, 2012

We are as Gods and have to get Good at it [video]

Posted by in categories: climatology, complex systems, engineering, ethics, existential risks, futurism, geopolitics, homo sapiens, human trajectories, philosophy, sustainability

The shift that has happened in 40 years which mainly has to do with climate change. Forty years ago, I could say in the Whole Earth Catalog, “we are as gods, we might as well get good at it”. Photographs of earth from space had that god-like perspective.

What I’m saying now is we are as gods and have to get good at it. Necessity comes from climate change, potentially disastrous for civilization. The planet will be okay, life will be okay. We will lose vast quantities of species, probably lose the rain forests if the climate keeps heating up. So it’s a global issue, a global phenomenon. It doesn’t happen in just one area. The planetary perspective now is not just aesthetic. It’s not just perspective. It’s actually a world-sized problem that will take world sized solutions that involves forms of governance we don’t have yet. It involves technologies we are just glimpsing. It involves what ecologists call ecosystem engineering. Beavers do it, earthworms do it. They don’t usually do it at a planetary scale. We have to do it at a planetary scale. A lot of sentiments and aesthetics of the environmental movement stand in the way of that.

Continue reading “We are as Gods…” and watch the video interview

Oct 8, 2012

Congratulations SpaceX

Posted by in categories: engineering, finance, open source, scientific freedom, space

The New York Time reported Space Exploration Technologies of Hawthorne, Calif. — SpaceX, for short — launched its Falcon 9 rocket on schedule at 8:35 p.m. Eastern time from Cape Canaveral, Fla.

The Wall Street Journal reported, “trouble-free countdown followed by liftoff at 8:35 p.m. ET, precisely as scheduled.”

Maj. Gen. Charles F. Bolden Jr., the NASA administrator said, “It actually marks the beginning of true commercial spaceflight to take cargo to the International Space Station for us.”

This is a milestone in the relationship between public and private enterprise. The handoff of what public enterprise, NACA/NASA, pioneered, developed and brought to maturity, to private enterprises capable of lowering the costs of space travel with ambitions to do more than stay in low earth orbit.

Congratulations, to Elon Musk, who believed it was possible, and went ahead and proved all the nay sayers wrong. This is an example of how one man’s vision and tenacity has changed the way we perceive the world. Congratulations!

Oct 7, 2012

50 months to avoid climate disaster – and a change is in the air

Posted by in category: sustainability

At the halfway point to a climate gamble, 50 contributor ideas give just a taste of the creativity and innovation available to us

“One or other of us will have to go,” Oscar Wilde is supposed to have said on his deathbed to the hated wallpaper in his room. The perilous acceleration of Arctic ice loss, and the imminent threat of irreversible climate change poses a similar ultimatum to the economic system that is pushing us over the brink. For society’s sake I hope this time we redecorate.

Fortunately, many people are queuing up to propose better designs, rather than just cursing the interiors, as you can read about here.

Monday 1 October marks the halfway point in a 100-month countdown to a game of climate roulette.

Continue reading “50 months to avoid climate disaster – and a change is in the air” »

Oct 7, 2012

Debunking Pulse Detonation Engines — Yes, No, Maybe

Posted by in categories: business, defense, engineering, military, nuclear weapons, physics, space, treaties

Previous posting in this Debunking Series.

In this post we will look at the last three types of engines. Can these engine technologies be debunked?

Start with the boring stuff. Nuclear/plasma engines. For more information look up Franklin Chang-Diaz’s Variable Specific Impulse Magnetoplasma Rocket (VASIMR). Real. Cannot be debunked.

Now for the more interesting stuff. The second is Pulse Detonation Engines (PDE). This type of engine uses detonation waves to combust fuel and oxidizer mixture. “The engine is pulsed because the mixture must be renewed in the combustion chamber between each detonation wave initiated by an ignition source.” Theoretically this type of engine is capable of speeds from subsonic to Mach 5.

Continue reading “Debunking Pulse Detonation Engines — Yes, No, Maybe” »

Oct 6, 2012

The decaying web and our disappearing history

Posted by in categories: information science, media & arts, philosophy

On January 28 2011, three days into the fierce protests that would eventually oust the Egyptian president Hosni Mubarak, a Twitter user called Farrah posted a link to a picture that supposedly showed an armed man as he ran on a “rooftop during clashes between police and protesters in Suez”. I say supposedly, because both the tweet and the picture it linked to no longer exist. Instead they have been replaced with error messages that claim the message – and its contents – “doesn’t exist”.

Few things are more explicitly ephemeral than a Tweet. Yet it’s precisely this kind of ephemeral communication – a comment, a status update, sharing or disseminating a piece of media – that lies at the heart of much of modern history as it unfolds. It’s also a vital contemporary historical record that, unless we’re careful, we risk losing almost before we’ve been able to gauge its importance.

Consider a study published this September by Hany SalahEldeen and Michael L Nelson, two computer scientists at Old Dominion University. Snappily titled “Losing My Revolution: How Many Resources Shared on Social Media Have Been Lost?”, the paper took six seminal news events from the last few years – the H1N1 virus outbreak, Michael Jackson’s death, the Iranian elections and protests, Barack Obama’s Nobel Peace Prize, the Egyptian revolution, and the Syrian uprising – and established a representative sample of tweets from Twitter’s entire corpus discussing each event specifically.

It then analysed the resources being linked to by these tweets, and whether these resources were still accessible, had been preserved in a digital archive, or had ceased to exist. The findings were striking: one year after an event, on average, about 11% of the online content referenced by social media had been lost and just 20% archived. What’s equally striking, moreover, is the steady continuation of this trend over time. After two and a half years, 27% had been lost and 41% archived.

Continue reading “The decaying web and our disappearing history”

Oct 5, 2012

Want to Get 70 Billion Copies of Your Book In Print? Print It In DNA

Posted by in categories: biological, biotech/medical, chemistry, futurism, information science, media & arts

I have been meaning to read a book coming out soon called Regenesis: How Synthetic Biology Will Reinvent Nature and Ourselves. It’s written by Harvard biologist George Church and science writer Ed Regis. Church is doing stunning work on a number of fronts, from creating synthetic microbes to sequencing human genomes, so I definitely am interested in what he has to say. I don’t know how many other people will be, so I have no idea how well the book will do. But in a tour de force of biochemical publishing, he has created 70 billion copies. Instead of paper and ink, or pdf’s and pixels, he’s used DNA.

Much as pdf’s are built on a digital system of 1s and 0s, DNA is a string of nucleotides, which can be one of four different types. Church and his colleagues turned his whole book–including illustrations–into a 5.27 MB file–which they then translated into a sequence of DNA. They stored the DNA on a chip and then sequenced it to read the text. The book is broken up into little chunks of DNA, each of which has a portion of the book itself as well as an address to indicate where it should go. They recovered the book with only 10 wrong bits out of 5.27 million. Using standard DNA-copying methods, they duplicated the DNA into 70 billion copies.

Scientists have stored little pieces of information in DNA before, but Church’s book is about 1,000 times bigger. I doubt anyone would buy a DNA edition of Regenesis on Amazon, since they’d need some expensive equipment and a lot of time to translate it into a format our brains can comprehend. But the costs are crashing, and DNA is a far more stable medium than that hard drive on your desk that you’re waiting to die. In fact, Regenesis could endure for centuries in its genetic form. Perhaps librarians of the future will need to get a degree in biology…

Link to Church’s paper

Source

Oct 4, 2012

How do you debunk this?

Posted by in categories: defense, engineering, finance, particle physics, physics, scientific freedom, space

Previous post in this Debunking Series.

——-

This video was broadcast on G4TV, September 19th 2012.

http://www.g4tv.com/videos/60838/dr-eric-w-davis-on-new-ligh…g-science/

Continue reading “How do you debunk this?” »

Oct 2, 2012

In Conversation with Albert-lászló Barabási on Thinking in Network Terms

Posted by in categories: complex systems, information science

One question that fascinated me in the last two years is, can we ever use data to control systems? Could we go as far as, not only describe and quantify and mathematically formulate and perhaps predict the behavior of a system, but could you use this knowledge to be able to control a complex system, to control a social system, to control an economic system?

We always lived in a connected world, except we were not so much aware of it. We were aware of it down the line, that we’re not independent from our environment, that we’re not independent of the people around us. We are not independent of the many economic and other forces. But for decades we never perceived connectedness as being quantifiable, as being something that we can describe, that we can measure, that we have ways of quantifying the process. That has changed drastically in the last decade, at many, many different levels.

Continue reading “Thinking in Network Terms” and watch the hour long video interview

Oct 2, 2012

Evolution in a Toxic World

Posted by in categories: biological, evolution

Earth is a hostile place — and that’s even before one starts attending school. Even when life first sparked into being, it had to evolve defenses to deal with a number of toxins, such as damaging ultraviolet light, then there were toxic elements ranging from iron to oxygen to overcome, later, there was DDT and other toxic chemicals and of course, there are all those dreaded cancers.

In Evolution In A Toxic World: How Life Responds To Chemical Threats [Island Press; 2012: Guardian Bookshop; Amazon UK;Amazon US], environmental toxicologist Emily Monosson outlines three billion years of evolution designed to withstand the hardships of living on this deadly planet, giving rise to processes ranging from excretion, transformation or stowing harmful substances. The subtitle erroneously suggests these toxins are only chemical in nature, but the author actually discusses more than this one subclass of toxins.

The method that arose to deal with these toxins is a plethora of specialised, targeted proteins — enzymes that capture toxins and repair their damages. By following the origin and progression of these shared enzymes that evolved to deal with specific toxins, the author traces their history from the first bacteria-like organisms to modern humans. Comparing the new field evolutionary toxicology to biomedical research, Dr Monosson notes: “In light of evolution, biomedical researchers are now asking questions that might seem antithetical to medicine”.

Continue reading “Evolution in a Toxic World”