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The researchers took T cells from the tumour, removed PD-1, multiplied the T cells and put them back into the mice and found that the tumours shrank.

They then inserted the enzyme and found that these T cells were able to keep up the fight at the tumour site.

The team is preparing for clinical trials and has started a company, PanTher Therapeutics, to develop the implant for patient use.

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Nice


Authors of the new study included The Scripps Research Institute’s (left to right)  Research Associate Ze Liu, Research Associate Yunchao Gai and Chair of the Department of Neuroscience Ron Davis.Researchers from The Scripps Research Institute (TSRI) identified a gene that suppresses memory in the brain cells of fruit flies, and the findings could provide targets for potential new treatments for neurodegenerative diseases like Alzheimer’s.

The team, led by Ron Davis, chair of TSRI’s Department of Neuroscience scanned about 3,500 Drosophila genes, and found multiple dozen memory suppressor genes that help the brain prioritize information and keep certain important memories.

The gene known as DmSLC22A was of particular interest, and when the team disabled it they found the flies’ memory improved nearly two-fold. “The fact that this gene is active in the same pathway as several cognitive enhancers currently used for the treatment of Alzheimer’s disease suggests it could be a potential new therapeutic target,” Davis said in a prepared statement.

Nthing new; nice to see more folks waking up.


We’re moving beyond just prosthetics and wearable tech. Soon, we’ll all by cyborgs in one way or another.

From The Six Million Dollar Man to Inspector Gadget to Robocop, humans with bionic body parts have become commonplace in fiction. In the real world, we use technology to restore functionality to missing or defective body parts; in science fiction, such technology gives characters superhuman abilities. The future of cyborgs may hinge on that distinction.

The Defense Advanced Research Projects Agency (DARPA) plans to develop a brain implant that links human brains to computers. Under the Obama administration’s Brain Initiative, DARPA has developed eight programs designed to enhance human physical and cognitive capabilities. The Neural Engineering System Design program seeks to “bridge the bio-electronic divide” via a small implant that acts as a translator between the brain and the digital world, giving humans improved sight and hearing.

Breaking the stereotype stigma; great article on CAN PM. I love it when folks break the boundaries and stereotypes that society often places on groups.


Canadian Prime Minister Justin Trudeau proved he’s more than just a pretty face when he wowed a room full of reporters and physicists with his knowledge of quantum computing.

The dashing politician was delivering his budget announcement at a press conference at the Perimeter Institute for Theoretical Physics Waterloo in Ontario, when he was put on the spot by a journalist.

The reporter opened his question by joking ‘I was was going to ask you about quantum computing, but …’ He then went onto ask the PM about Canada’s fight against ISIS.

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University of Tokyo researchers have created an ultrathin and ultraflexible organic e-skin that supports PLED and OLED displays.

Researchers from the University of Tokyo have created a protective layer of organic material that’s ultrathin and ultraflexible. And the have demonstrated the material’s usefulness by making an OLED display that’s air-stable. This opens the possibility of developing better electronic skin displays, the next major leap in wearable technology.

The thickness (or rather, thinness) and flexibility of wearable electronics is an essential factor in its further development. Plastic substrates are commonly used in the creation of such devices, which still require millimeter-scale thick glass. Also, whenever micrometer-scale and flexible organic materials are developed, they aren’t reliably stable when exposed to air.

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