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Ever since Kepler’s observation in the 17th century that sunlight is one of the reasons that the tails of comets to always face away from the sun, it has been understood that light exerts pressure in the direction it propagates. Radiation pressure is produced by the momentum carried by light, and it plays a crucial role in a variety of systems, from atomic to astronomical scales.

In a recent theoretical paper, a group from the RIKEN Center for Emergent Matter Science in Japan showed that density in non-uniform optical fields has an unusual component, which is orthogonal to the propagation direction of and is proportional to the optical spin, which means the degree of circular polarization. They predicted that this spin momentum would produce a transverse spin-dependent optical force, a few orders of magnitude weaker than the usual .

Now, based on the theoretical work, a group from RIKEN, the University of Bristol, and other institutions have used an extremely precise technique to experimentally verify that light does in fact exert the extraordinary perpendicular force, which is determined by the polarization of the light. The research has been published in Nature Physics.

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Hyderabad: Infections, haemorrhage, swelling and head injuries are some of the prime reasons for brain surgery but experts say taking the patient under the knife is the last option because of the complexities of the procedure which could lead to disability or death.

Senior doctors said despite advancements in technology, dealing with brain surgeries requires much expertise and continues to be a challenging area.

Senior neurosurgeon Dr Radha Krishna said, “Brain surgeries are complex and the protocol is to first opt for medicines. Nowadays due to diagnostic technologies, even the smallest of lesions or tumours are picked up but it is still important to treat them with medicines.”

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A team of researchers has found a key player in brain tumour formation that may lead to new therapies for a deadly and incurable cancer.

The study published in Nature Neuroscience is the first to show that a protein called OSMR (Oncostatin M Receptor) is required for glioblastoma tumours to form.

Glioblastoma is one of the most deadly cancers, resistant to radiation, chemotherapy and difficult to remove with surgery.

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This makes me a little nervous because pathways are very fragile and just the smallest change can result is some very bad/ even devastating results in other areas of the brain/ body.

Alzheimer’s remains one of the costliest yet most mysterious conditions in the United States, where an estimated 5.1 million Americans are living with the incurable, progressive disease. But researchers at The Rockefeller University have found that manipulating a protein pathway linked with Alzheimer’s helped improve memory impairment in mice— a finding that offers hope for new treatment in humans. Memory loss is the hallmark symptom of the disease.

Scientists with the Fisher Center for Alzheimer’s Research Foundation at The Rockefeller University used a complex set of imaging technologies and experiments to identify an early trafficking protein pathway (COPI) that affects amyloid precursor protein (APP), which precedes the formation of amyloid plaques. Previous research on Alzheimer’s have targeted this plaque, but scientists haven’t successfully identified a way to halt its progression. There is currently no cure or effective treatment for the disease.

Alzheimer’s Disease Mortality by State | HealthGrove.

Continue reading “Interfering with brain pathway early could improve memory in Alzheimer’s patients” | >

Change is good; looks like we’re about to re-review some existing simulation codes around Quantum Mechanic Simulation.

Researchers show that new generations of quantum mechanical simulation codes agree better than earlier generations’. The study appears in Science.

Several international scientists from over 30 universities and institutes teamed to investigate to what extent quantum simulations of material properties agree when they are performed by different researchers and with different software. Torbjörn Björkman from Åbo Akademi participated from Finland. Björkman has previously worked at COMP Centre of Excellende at Aalto University. “A group of researchers compared the codes, and the results we got were more precise than in any other calculations before,” he said.

The possibility to produce identical results in independent yet identical researches is a corner stone of science. Only in this way science can identify ‘laws’, which lead to new insights and new technologies. However, several recent studies have pointed out that such reproducibility does not always come spontaneously. Even predictions by computer codes require caution, since the way in which theoretical models are implemented may affect simulation results.

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Nice; taking design and manufacturing to new levels.

Advanced materials are increasingly embodying counterintuitive properties, such as extreme strength and super lightness, while additive manufacturing and other new technologies are vastly improving the ability to fashion these novel materials into shapes that would previously have been extremely costly or even impossible to create. Generating new designs that fully exploit these properties, however, has proven extremely challenging. Conventional design technologies, representations, and algorithms are inherently constrained by outdated presumptions about material properties and manufacturing methods. As a result, today’s design technologies are simply not able to bring to fruition the enormous level of physical detail and complexity made possible with cutting-edge manufacturing capabilities and materials.

To address this mismatch, DARPA today announced its TRAnsformative DESign (TRADES) program. TRADES is a fundamental research effort to develop new mathematics and algorithms that can more fully take advantage of the almost boundless design space that has been enabled by new materials and fabrication methods.

“The structural and functional complexities introduced by today’s advanced materials and manufacturing methods have exceeded our capacity to simultaneously optimize all the variables involved,” said Jan Vandenbrande, DARPA program manager. “We have reached the fundamental limits of what our computer-aided design tools and processes can handle, and need revolutionary new tools that can take requirements from a human designer and propose radically new concepts, shapes and structures that would likely never be conceived by even our best design programs today, much less by a human alone.”

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