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Interesting read for those interested in inorganic protein (NP) states from a solid to a liquid as the research proves inorganic NPs are in a ‘glassy’ state while transitioning from a solid to a liquid form.


Molecular dynamics simulations of ubiquitin in water/glycerol solutions are used to test the suggestion by Karplus and coworkers that proteins in their biologically active state should exhibit a dynamics similar to ‘surface-melted’ inorganic nanoparticles (NPs). Motivated by recent studies indicating that surface-melted inorganic NPs are in a ‘glassy’ state that is an intermediate dynamical state between a solid and liquid, we probe the validity and significance of this proposed analogy. In particular, atomistic simulations of ubiquitin in solution based on CHARMM36 force field and pre-melted Ni NPs (Voter-Chen Embedded Atom Method potential) indicate a common dynamic heterogeneity, along with other features of glass-forming (GF) liquids such as collective atomic motion in the form of string -like atomic displacements, potential energy fluctuations and particle displacements with long range correlations (‘colored’ or ‘pink’ noise), and particle displacement events having a power law scaling in magnitude, as found in earthquakes. On the other hand, we find the dynamics of ubiquitin to be even more like a polycrystalline material in which the α-helix and β-sheet regions of the protein are similar to crystal grains so that the string -like collective atomic motion is concentrated in regions between the α-helix and β-sheet domains.

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For fellow innovators and private scientists who dream and believe in your dream.


Rule 3: Their Ideas Look Like Failure In The Beginning

When innovators share what they’re working on early in the process, they open the floodgates to premature criticism. This is only natural considering that innovation stems from a singular vision that no one else sees yet.

Seasoned innovators have learned through experience to be wary of upfront collaboration. It’s difficult to explain motives around an intangible concept, especially considering that, by definition, they can’t point to others who are doing the same thing.

With the work we are doing on cell circuitry technology and Quantum; these implants will become more and more seamless in all living things.


A biosensor developed in Clemson University, South Carolina, funded by the U.S. Department of Defense, will be able to transmit information regarding blood lactate and glucose levels of a wounded soldier or of other injured patients. The biochip will be implanted in the patient’s body for a short time and will wirelessly transmit the levels of lactate and glucose to the medical staff.

The biochip, sized 2mm x 4mm x 0.5mm, is a dual sensing element coated with hydrogels to prevent it from being rejected by human tissue. The sensor has the ability to transmit life saving readings to the medical personnel. The implantation of the chip will only be temporary, although long term biochip implants are also being tested and may be used as a precaution in some cases.

Blood glucose and lactate levels are very important for medical staff in the first stages of dealing with a trauma patient. These measurements can imply what the oxygen level in the patients’ blood is and can indicate the overall metabolic state of the patient. The blood lactate level is sometimes used to determine whether or not a trauma patient can survive surgery. Getting these measurements in real time can help the medics in a hospital or out in the field make decisions much faster and by doing so will help save lives.

Nice.


Researchers at the University of Central Florida (UCF) in the US are combining nanoscience with the principle of Faraday rotation, a magnetic phenomenon discovered in 1845, in a new method for speedy medical tests.

The team applied the magneto-optical technique, called frequency-domain Faraday rotation spectroscopy—or fd-FRS, to characterize proteins, using antibody-functionalized magnetic nanoparticles (MNPs).

“Fd-FRS is a new way of looking at the interaction between light and magnetized material,” says Shawn Putnam, assistant professor UFC’s College of Engineering & Computer Science. “We covered the surfaces of magnetic nanoparticles with a layer of biological sensors and measured their movement after exposure to their corresponding biological targets for detection.”

Nice read & video illustration.


Quantum entanglement may appear to be closer to science fiction than anything in our physical reality. But according to the laws of quantum mechanics — a branch of physics that describes the world at the scale of atoms and subatomic particles — quantum entanglement, which Einstein once skeptically viewed as “spooky action at a distance,” is, in fact, real.

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Quantum’s natural selection explored.


There might be no getting around what Albert Einstein called “spooky action at a distance.” With an experiment described today in Physical Review Letters — a feat that involved harnessing starlight to control measurements of particles shot between buildings in Vienna — some of the world’s leading cosmologists and quantum physicists are closing the door on an intriguing alternative to “quantum entanglement.”

“Technically, this experiment is truly impressive,” said Nicolas Gisin, a quantum physicist at the University of Geneva who has studied this loophole around entanglement.

According to standard quantum theory, particles have no definite states, only relative probabilities of being one thing or another — at least, until they are measured, when they seem to suddenly roll the dice and jump into formation. Stranger still, when two particles interact, they can become “entangled,” shedding their individual probabilities and becoming components of a more complicated probability function that describes both particles together. This function might specify that two entangled photons are polarized in perpendicular directions, with some probability that photon A is vertically polarized and photon B is horizontally polarized, and some chance of the opposite. The two photons can travel light-years apart, but they remain linked: Measure photon A to be vertically polarized, and photon B instantaneously becomes horizontally polarized, even though B’s state was unspecified a moment earlier and no signal has had time to travel between them.

When light shines on certain materials, it causes them to emit electrons. This is called “photoemission” and it was discovered by Albert Einstein in 1905, winning him the Nobel Prize. But only in the last few years, with advancements in laser technology, have scientists been able to approach the incredibly short timescales of photoemission. Researchers at EPFL have now determined a delay of one billionth of one billionth of a second in photoemission by measuring the spin of photoemitted electrons without the need of ultrashort laser pulses. The discovery is published in Physical Review Letters.

Photoemission

Photoemission has proven to be an important phenomenon, forming a platform for cutting-edge spectroscopy techniques that allow scientists to study the properties of electrons in a solid. One such property is spin, an intrinsic quantum property of particles that makes them look like as if they were rotating around their axis. The degree to which this axis is aligned towards a particular direction is referred to as spin polarization, which is what gives some materials, like iron, magnetic properties.

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Our story on QC just keeps advancing as I cannot wait to see this technology on our smart devices.


Holographic atomic memory, invented and constructed by physicists from the Faculty of Physics at the University of Warsaw, is the first device able to generate single photons on demand in groups of several dozen or more. The device, successfully demonstrated in practice, overcomes one of the fundamental obstacles towards the construction of some type of quantum computer.

Completely secure, high-speed quantum communication, or even a model of quantum computer, may be among the possible applications for the new source of single photons recently built at the Faculty of Physics at the University of Warsaw (UW Physics), Poland. An unprecedented feature of this new device is that for the first time it enables the on-demand production of a precisely controlled group of photons, as opposed to just a single one.

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