Lifeboat Foundation

View show notes here: https://bit.ly/3GJjQKz Become a member to receive exclusive content: https://peterattiamd.com/subscribe/ Sign up to receive Peter’s email newsletter: https://peterattiamd.com/newsletter/ Colleen Cutcliffe is an expert in molecular biology and co-founder of Pendulum Therapeutics, a company working to develop treatments for a variety of diseases by targeting the microbiome. In this episode, Colleen delves into the complexity of the microbiome, how it is tested, and how it changes over time. She explores how probiotics, prebiotics, and postbiotics affect the gut and makes a compelling case that well-developed products have the potential not only to enhance gut health but also to positively influence overall metabolic well-being. Colleen emphasizes the significance of a high-fiber diet in sustaining a thriving gut microbiome, shares insights on minimizing microbiome damage during antibiotic use, provides tips for fostering and preserving a healthy gut, and much more. We discuss: 0:00:00 — Intro 0:00:34 — Colleen’s background and current focus 0:03:08 — The basics of the microbiome 0:12:37 — The study of the human microbiome 0:17:42 — Categories of bacteria, and the implications on health of the rapid evolution of bacteria 0:27:51 — Methods for measuring and understanding the microbiome, and key indicators of microbiome health 0:39:52 — The important role of fiber for promoting gut health through the production of butyrate 0:47:21 — The case for manipulating gut bacteria via fecal microbiota transplant (FMT) 0:53:25 — Dynamics of the microbiome: the gut-brain connection and how antibiotics, nutrition, stress, and more impact the microbiome’s diversity and function 0:59:16 — Factors that influence the vaginal microbiom 1:03:46 — The effect of gut microbes on obesity and challenges with fecal transplants in people 1:06:25 — Beneficial strains of gut bacteria and strains commonly found in probiotics 1:16:35 — The difference between a probiotic and prebiotic, and how CFUs are a measure of the “active ingredient” 1:21:47 — Considerations about how probiotic strains are produced, and more on the meaning of CFU 1:31:12 — Mitigating the effect of antibiotics on the microbiome 1:39:58 — What do we know about the effect of artificial sweeteners on the gut microbiome? 1:47:02 — Why Akkermansia is a keystone strain with implications for metabolic health and an individual’s response to dietary interventions 1:58:14 — The essential steps necessary to develop a robust probiotic for optimal health support 2:01:45 — How Akkermansia helps control blood glucose, and potential implications of Akkermansia in weight loss, diabetes management, and more 2:22:46 — Pendulum Therapeutics’ commitment to rigorous product develop 2:29:54 — Details about the probiotic “Glucose Control” and other probiotics developed by Pendulum Therapeutics 2:38:43 — Further studies of Akkermansia that have been proposed or are underway ——– About: The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, and all that goes into that from physical to cognitive to emotional health. With over 70 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, and much more. Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan.

Welcome for another episode of Health Theory! This episode promises to deliver a riveting conversation with the master of fitness, Andy Galpin. Andy is not just your average exercise physiologist, professor, and researcher. He’s a true powerhouse with a trademark ability to seamlessly bridge the gap between academic knowledge and real-world application.

Dr. Jordan B. Peterson and Andrew Huberman discuss neurology, the way humans and animals react to specific stimuli, and how this knowledge can be utilized for personal growth.

Today we react to “How to Destroy the Universe” from the amazing Kurzgesagt — In a Nutshell. Please support Kurzgesagt and make sure to check out the original…

Our brains are remarkably energy efficient.

Using just 20 watts of power, the human brain is capable of processing the equivalent of an exaflop — or a billion-billion mathematical operations per second.

Now, researchers in Australia are building what will be the world’s first supercomputer that can simulate networks at this scale.

Aizip’s breakthrough starts with sneakers and then…who knows.

Some researchers argue that looking for structural changes in sugar molecules called glycans could help identify different types of cancer early on.

Companies and countries are in a race to develop quantum computers. The machines could revolutionize problem solving in medicine, physics, chemistry and engineering.

Causality is key to our experience of reality: dropping a glass, for example, causes it to smash, so it can’t smash before it’s dropped. But in the quantum world those rules don’t necessarily apply, and scientists have now demonstrated how that weirdness can be harnessed to charge a quantum battery.

In a sense, you could say that quantum batteries are powered by paradoxes. On paper, they work by storing energy in the quantum states of atoms and molecules – but of course, as soon as the word “quantum” enters the conversation you know weird stuff is about to happen. In this case, a new study has found that quantum batteries could work by violating cause-and-effect as we know it.

“Current batteries for low-power devices, such as smartphones or sensors, typically use chemicals such as lithium to store charge, whereas a quantum battery uses microscopic particles like arrays of atoms,” said Yuanbo Chen, an author of the study. “While chemical batteries are governed by classical laws of physics, microscopic particles are quantum in nature, so we have a chance to explore ways of using them that bend or even break our intuitive notions of what takes place at small scales. I’m particularly interested in the way quantum particles can work to violate one of our most fundamental experiences, that of time.”