Lifeboat Foundation: Safeguarding Humanity
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Blog – Page 11039

The University of Queensland Australia has done subsequent studies on time travel, its possibility aspects, and components. According to in-depth studies from the University, time travel is a possibility. The scientists used single particles of light photons to simulate quantum particles that travel through time. The study indicated that modern physics has strange aspects that were explained by Professor Timothy Ralph. Quantum particles are made up of fuzzy or uncertain components that make it possible for them to wiggle around and thus avoid inconsistent time travel situations. Therefore, nature behaves differently making the impossible possible.

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In Brief

  • Illumina claims its new NovaSeq sequencing machine will one day be able to sequence an entire genome for less than $100, a process that currently costs about $1,000.
  • Cheaper genome sequencing could revolutionize healthcare, allowing doctors to prescribe individualized treatment options for patients.

There are an estimated 25,000 genes in the human genome, comprised of approximately 3 billion nucleotide base pairs. It took the Human Genome Project (HGP) approximately 15 years and $2.7 billion to sequence the entire human genome (minus about 1 percent) using the DNA of several volunteers.

Now, San Diego-based sequencing company Illumina has debuted a new sequencing machine, the NovaSeq (NovaSeq 5000 and NovaSeq 6000), that it says will one day be able to sequence an entire genome for less than $100 in fewer than 60 minutes. This is a steep difference in both cost and time compared to that first sequenced genome, but it follows the trend. In 2006, Illumina released their first machine, which could sequence a genome for $300,000, but by last year, that price had dropped to $1,000.

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Senolytics to remove senescent cells will deliver the first “repair” based approach to treat the aging process. This is the arrival of true rejuvenation biotechnology in the SENS model of damage repair.

Senescent cell removal with companies such as Unity, entering human clinical trials in the next 18 months will deliver the first true damage repair rejuevenation biotechnology. This will be the first “repair” approach to the aging process and one the SENS Research Foundation has been advocating for over a decade.

#aging #crowdfundthecure

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This is probably important.

Scientists at The Scripps Research Institute (TSRI) have discovered a protein that fine-tunes the cellular clock involved in aging.

This novel , named TZAP, binds the ends of chromosomes and determines how long , the segments of DNA that protect chromosome ends, can be. Understanding telomere length is crucial because telomeres set the lifespan of cells in the body, dictating critical processes such as aging and the incidence of cancer.

“Telomeres represent the clock of a cell,” said TSRI Associate Professor Eros Lazzerini Denchi, corresponding author of the new study, published online today in the journal Science. “You are born with telomeres of a certain length, and every time a cell divides, it loses a little bit of the telomere. Once the telomere is too short, the cell cannot divide anymore.”

Continue reading “Scientists discover master regulator of cellular aging” | >

Epigenetic changes are not all reset with iPS thankfully science has recently demonstrated a technique for reversing that too. The future is looking bright for stem cell quality improvements.

Reprogramming stem cells back to a functionally younger state is not a pefect process and epigenetic changes and mutations remain in place tainting the cells and reducing their quality.

Scientists working in the stem cell field will no doubt be finding ways to work around this and indeed recent work at SALK could reset epigenetic changes in these cells so solutions are within reach in the next few years.

“When adult cells are reprogrammed into induced pluripotent stem cells (IPSCs), they appear to carry marks of their age.”

Continue reading “Donor Age Shows Up In Induced Stem Cells” | >

Motor neurons are vital cells that facilitate muscle contraction and also affect sensation. In diseases like ALS and spinal muscular atrophy, motor cells are plagued with mutations that cause degrees of paralysis and pain in patients. In a study detailed in Cell Stem Cell, scientists developed a mechanism to directly reprogram stem cells into motor neurons.

Cell reprogramming is a novel exploration in medical studies that could treat numerous diseases by growing the body’s own stem cells into healthy cells. The mechanism of reprogramming, however, has just begun to be understood.

The researchers elucidated a new pathway for cell reprogramming by analyzing gene transcription in mice. As established by previous studies, reprogramming is brought about by a series of transcriptions, AKA, how the genes control the expression of other genes.

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