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While some quantum computing companies push to demonstrate near-term commercial value, Rigetti Computing is taking a different approach. The company has identified specific technical milestones it said must be achieved before quantum systems can deliver meaningful business results, including 99.9% fidelity, 20-nanosecond gate speeds and real-time error correction.

In an interview we conducted at The Economist Commercializing Quantum event, Rigetti CEO Subodh Kulkarni outlined how the company’s novel chiplet-based architecture could help scale systems to 10,000 qubits, while also revealing an intriguing potential role for quantum computing in advancing artificial general intelligence.

Enter Quantum: What’s your take on the debate between return on investment versus technical capability in quantum computing?

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The phenomenon of biological ultraweak photon emission (UPE), that is, extremely low-intensity emission (10 − 103 photons/cm2/sec) in the spectral range of 200 − 1,000 nm, has been observed in all living systems that have been examined. Here we report experiments that exemplify the ability of novel imaging systems to detect variations in UPE for a set of physiologically important scenarios. We use EMCCD and CCD cameras to capture single visible-wavelength photons with low noise and quantum efficiencies higher than 90%. Our investigation reveals significant contrast between the UPE from live vs. dead mice. In plants we observed that an increase in temperature and injuries both caused an increase in UPE intensity. Moreover, chemical treatments modified the UPE emission characteristics of plants, particularly the application of an anesthetic (benzocaine) to injury, which showed the highest emission among the compounds tested. As a result, UPE imaging provides the possibility of non-invasive label-free imaging of vitality in animals and the responses of plants to stress.

The authors have declared no competing interest.

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A scientist from Tokyo Metropolitan University has solved the longstanding problem of a “dissonance” in gravitational waves emitted by a black hole.

Using high precision computing and a new theoretical physics framework, it was discovered that it was caused by a resonance between a pair of distinctive “modes” i.e. different ways in which a black hole can “ring.” The phenomenon offers new insights into the nascent field of black hole spectroscopy.

The research is published in the journal Physical Review Letters.

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Scientists at Northwestern University have developed a new approach that directly combats the progression of neurodegenerative diseases like Alzheimer’s disease and amyotrophic lateral sclerosis (ALS).

In these devastating illnesses, proteins misfold and clump together around brain cells, which ultimately leads to cell death. The innovative new treatment effectively traps the proteins before they can aggregate into the toxic structures capable of penetrating neurons. The trapped proteins then harmlessly degrade in the body.

The “clean-up” strategy significantly boosted the survival of lab-grown human neurons under stress from disease-causing proteins.

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Persuasion is a fundamental aspect of communication, influencing decision-making across diverse contexts, from everyday conversations to high-stakes scenarios such as politics, marketing, and law. The rise of conversational AI systems has significantly expanded the scope of persuasion, introducing both opportunities and risks. AI-driven persuasion can be leveraged for beneficial applications, but also poses threats through manipulation and unethical influence. Moreover, AI systems are not only persuaders, but also susceptible to persuasion, making them vulnerable to adversarial attacks and bias reinforcement. Despite rapid advancements in AI-generated persuasive content, our understanding of what makes persuasion effective remains limited due to its inherently subjective and context-dependent nature. In this survey, we provide a comprehensive overview of computational persuasion, structured around three key perspectives: AI as a Persuader, which explores AI-generated persuasive content and its applications; AI as a Persuadee, which examines AI’s susceptibility to influence and manipulation; and AI as a Persuasion Judge, which analyzes AI’s role in evaluating persuasive strategies, detecting manipulation, and ensuring ethical persuasion. We introduce a taxonomy for computational persuasion research and discuss key challenges, including evaluating persuasiveness, mitigating manipulative persuasion, and developing responsible AI-driven persuasive systems. Our survey outlines future research directions to enhance the safety, fairness, and effectiveness of AI-powered persuasion while addressing the risks posed by increasingly capable language models.

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New research by scientists at the University of Toronto and the Structural Genomics Consortium has deepened our understanding of how viruses like the flu, common cold, and COVID-19 get into cells in human airways.

Using the Canadian Light Source at the University of Saskatchewan, the researchers identified for the first time the crystal structures of a human protein (TMPRSS11D) that viruses use as a doorway into our body. The study is published in the journal Nature Communications.

Understanding how viruses use our proteins to gain entry into our cells will help researchers develop better ways to stop infections in their tracks.

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Current dental implants can work well, but they’re not perfect. They don’t attach to bones and gums in the same way that real teeth do. And around 20% of people who get implants end up developing an infection called peri-implantitis, which can lead to bone loss.

It is all down to the microbes that grow on them. There’s a complex community of microbes living in our mouths, and disruptions can lead to infection. But these organisms don’t just affect our mouths; they also seem to be linked to a growing number of disorders that can affect our bodies and brains. If you’re curious, read on.

The oral microbiome, as it is now called, was first discovered in 1670 by Antonie van Leeuwenhoek, a self-taught Dutch microbiologist. “I didn’t clean my teeth for three days and then took the material that had lodged in small amounts on the gums above my front teeth … I found a few living animalcules,” he wrote in a letter to the Royal Society at the time.

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