Lifeboat Foundation

We all become accustomed to the tone and pattern of human speech at an early age, and any deviations from what we have come to accept as “normal” are immediately recognizable. That’s why it has been so difficult to develop text-to-speech (TTS) that sounds authentically human. Google’s DeepMind AI research arm has turned its machine learning model on the problem, and the resulting “WaveNet” platform has produced some amazing (and slightly creepy) results.

Google and other companies have made huge advances in making human speech understandable by machines, but making the reply sound realistic has proven more challenging. Most TTS systems are based on so-called concatenative technologies. This relies upon a database of speech fragments that are combined to form words. This tends to sound rather uneven and has odd inflections. There is also some work being done on parametric TTS, which uses a data model to generate words, but this sounds even less natural.

DeepMind is changing the way speech synthesis is handled by directly modeling the raw waveform of human speech. The very high-level approach of WaveNet means that it can conceivably generate any kind of speech or even music. Listen above for an example of WaveNet’s voice synthesis. There’s an almost uncanny valley quality to it.

Continue reading “Google’s DeepMind develops creepy, ultra-realistic human speech synthesis” »

At Quora, I occasionally play, “Ask the expert”. Today, I was asked if the difference between quotes at various Bitcoin exchanges presents a profit opportunity.

In addition to my answer, one other cryptocurrency enthusiast offered pithy, one-line response: He said “Buy local, sell internationally and pocket the difference!” I tend to believe the opposite is more likely to generate profit: Buy internationally and sell locally. But, I am getting ahead of myself. Here is my answer [co-published at Quora]…

Question:
A Bitcoin exchange in my country quotes a different rate than
international markets. Can I profit from the price difference?

Answer:
Buying and selling a commodity with the intention of profiting from the difference in price in various markets, regions or exchanges is called arbitrage. Typically, the item must be widely traded and fungible. Although it can be a tangible item (one that must be delivered or stored, like gold, oil, frozen orange juice or soy beans), arbitrage is more practical when applied to an ‘item of account’, such as foreign currency, equity shares, stock futures, or Bitcoin.

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Interesting…

A transportable chemical reactor developed at Germany’s Karlsruhe Institute of Technology (KIT) and spinoff company Ineratec that uses solar power to convert CO₂ from the air and regenerative hydrogen from electrolysis into liquid fuels will be tested in a pilot plant.

A 14-year-old girl who said before dying of cancer that she wanted a chance to live longer has been allowed by the high court to have her body cryogenically frozen in the hope that she can be brought back to life at a later time.

The court ruled that the teenager’s mother, who supported the girl’s wish to be cryogenically preserved, should be the only person allowed to make decisions about the disposal of her body. Her estranged father had initially opposed her wishes.

During the last months of her life, the teenager, who had a rare form of cancer, used the internet to investigate cryonics. Known only as JS, she sent a letter to the court: “I have been asked to explain why I want this unusual thing done. I’m only 14 years old and I don’t want to die, but I know I am going to. I think being cryo‐preserved gives me a chance to be cured and woken up, even in hundreds of years’ time.

Continue reading “14-Year-Old Girl Who Died of Cancer Wins Right to be Cryogenically Frozen” »

In Brief As technology improves, the possibility that our world may be a simulated one is becoming more and more probable, argues Universe Today founder Fraser Cain. But can we ever prove that we live in a simulation of a reality?

All the world’s a stage. Or is it a simulation?

Continue reading “The Simulation Hypothesis: Is Reality All Just A Computer Simulation?” »

So much for “Junk” DNA being a load of old rubbish!

UC San Francisco researchers have taken a major step toward understanding the function of the tens of thousands of human genes that do not code for proteins, a phenomenon considered one of the key remaining mysteries of the human genome. New findings, which focused on the roles of these genes in human cancer cells, suggest a possible new strategy for targeting the disease.

In recent years, researchers have recognized that non-coding regions of the genome—long dismissed as “junk DNA”—are actually key players in cell biology, development, and disease. However, the vast majority of these regions have not yet been extensively studied.

Continue reading “CRISPR study reveals unexpected roles of non-coding RNAs” »

Stem cell bandages are in development in the UK.

A ‘living bandage’ made from stem cells, which could revolutionise the treatment and prognosis of a common sporting knee injury, has been trialled in humans for the first time by scientists at the Universities of Liverpool and Bristol.

Meniscal tears are suffered by over one million people a year in the US and Europe alone and are particularly common in contact sports like football and rugby. 90 per cent or more of tears occur in the white zone of meniscus which lacks a blood supply, making them difficult to repair. Many professional sports players opt to have the torn tissue removed altogether, risking osteoarthritis in later life.

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Further progress with cancer this time using genome sequencing.

In their search for new ways to treat cancer, many scientists are using a high-tech process called genome sequencing to hunt for genetic mutations that encourage tumor cells to thrive. To aid in this search, some researchers have developed new bioinformatics methods that each claim to help pinpoint the cancer-friendly mutants.

But a stubborn question remains: Among the numerous new tactics that aim to spotlight the so-called cancer driver genes, which produce the most accurate results?

Continue reading “New bioinformatics tool tests methods for finding mutant genes that ‘drive’ cancer” »

Hype aside demonstration that epigentic reprogramming can reverse some of the aging process is an important step forward for progress. We can expect to see this moving to human trials in the next decade or so making the future an exciting possibility.

Science is increasingly coming to the conclussion that aging is amenable to intervention and that it is a plastic process that we can manipulate. More research in this week shows that aging is indeed elastic and is not a one way process at all. The sooner society accepts what the data from the labs is showing the sooner we can cure age-related diseases for healthier longer lives!

“We did not correct the mutation that causes premature aging in these mice,” lead researcher Juan Carlos Izpisua Belmonte said in a recent statement. “We altered aging by changing the epigenome, suggesting that aging is a plastic process.”

Continue reading “Scientists Expand Mice Lifespans” »