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Microsoft today is unveiling new artificial intelligence technology that’s something of an artist – a “drawing bot.” The bot is capable of creating images from text descriptions of an object, but it also adds details to those images that weren’t included the text, indicating that the AI has a little imagination of its own, says Microsoft.

“If you go to Bing and you search for a bird, you get a bird picture. But here, the pictures are created by the computer, pixel by pixel, from scratch,” explained Xiaodong He, a principal researcher and research manager in the Deep Learning Technology Center at Microsoft’s research lab in Redmond, Washington, in Microsoft’s announcement. “These birds may not exist in the real world — they are just an aspect of our computer’s imagination of birds.”

The bot is able to generate a variety of images, researchers say, including everything from “ordinary pastoral scenes,” like those with grazing livestock, to the absurd – like “a floating double-decker bus.”

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Nearly 500 years ago in what we now call Mexico, a disease started rippling through the population. Red spots appeared on the skin, accompanied by wretched vomiting, bleeding from multiple orifices, and eventually, death. Combined with an invasion from Europe and horrific droughts, it was generally not a pleasant time or place to be alive.

It bore the name cocoliztli, meaning ‘pestilence,’ and it killed between five and 15 million people in just three years. As many plagues were at the time, it proved deadly and mysterious, burning through entire populations. Occurring centuries before John Snow’s work on cholera gave rise to epidemiology, data on the disease’s devastation was sparse. Over the years, researchers and historians attempted to pin the blame for the illness on measles, plague, viral hemorrhagic fevers like Ebola, and typhoid fever—a disease caused by a variation of the bacteria Salmonella enterica.

In a paper published this week in Nature Ecology & Evolution, researchers present evidence that the latter was the most likely candidate in this cast of microbial miscreants. The study was pre-printed in biorxiv last year. The researchers detected the genome of a different variety of Salmonella enterica (the specific variety is Paratyphi C) in teeth of individuals buried in a cemetery historically linked to the deadly outbreak.

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But it remains to be seen whether drug regulators will go along with a new way of making medicines. To do so, agencies like the U.S. Food and Drug Administration will need to rewrite their rules for validating the safety of medicines. Instead of signing off on the production facility and manufactured drug samples, regulators would have to validate that reactionware produces the desired medication. Cronin agrees it’s a hurdle. But he argues that future printed reactors could simply include a final module containing standard validation tests that produce a visual readout, much like a pregnancy test. “I think it’s manageable.”


Digitized chemistry on demand could also undermine drug counterfeiters.

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Looking back at best of 2017)


The finding was a milestone in the field of anti-aging science. Professor Judith Campisi, Ph.D., a celebrity in the anti-aging field, and lead author of the study remarked

“Imagine the possibility of taking a pill [rapamycin] for a few days or weeks every few years, as opposed to taking something with side effects every day for the rest of your life. It’s a new way of looking at how we could deal with age-related maladies.” – Judith Campisi, PhD

Campisi’s discovery suggests that a person could take rapamycin intermittently, say, once a week, shutting down the chronic inflammation. Because the zombie cells haven’t gone away, they will eventually find their footing and start the inflammatory ball rolling once again. A person on this regimen would repeat the dosage intermittently and substantially reduce inflammation.