Lifeboat Foundation

It sounds really obvious, but hospitals aren’t for healthy people. The world’s entire health system is really there to react once people get ill. If doctors are able to catch an illness at stage one that’s great, but if it reaches stage three or four there’s often not that much that can be done. So what if we could treat patients at stage zero and predict the likelihood of contracting diseases? We could then get treatment to people who need it much earlier and take preventative steps to avoid illness altogether.

Currently, when we think of monitoring in healthcare we’re usually referring to monitoring patients’ reactions to drugs or treatments, but this is changing. No amateur runner’s uniform is complete these days without a Fitbit or some kind of analytics tool to monitor progress, so the idea of monitoring the healthy is becoming ingrained in the public’s consciousness. But Fitbits only scrape the surface of what we can do. What if the data from fitness trackers could be combined with medical records, census data and the details of supermarket loyalty cards to predict the likelihood of contracting a particular disease?

With big data we can move from reacting to predicting, but how do we move beyond just making predictions; how do we prevent disease from occurring altogether? Up until now all of our monitoring technology has been located outside of the body, but nano-sized entities made of DNA could one day patrol the body, only acting when they come into contact with specific cells – cancer cells, for example. The technology that would turn tiny machines – roughly the size of a virus – into molecular delivery trucks that transport medication is already being worked on by bioengineers. If this kind of technology can be used to treat cancer, without needing to release toxic agents into the body, can the same technology be inserted into a healthy person and lie in wait for the opportunity to fight disease on its host’s behalf?

I have spent the last 30 years in various aspects of the biopharmaceutical industry, which for the most part has been a very rewarding experience.

However, during this time period, having been immersed many different components of therapeutic development and commercialization, one thing has always bothered me: a wide array of promising research never makes it off the bench to see the translational light of day, and gets lost in the historical scientific archives.

I always believed that scientific progress happened in a very linear narrative, with each new discovery supporting the next, resulting ultimately in an eventual stairway of scientific enlightenment.

Continue reading “Death Reversal — The Reanima Project — Research Whose Time Has Come” »

In SELF/LESS, a dying old man (Academy Award winner Ben Kingsley) transfers his consciousness to the body of a healthy young man (Ryan Reynolds). If you’re into immortality, that’s pretty good product packaging, no?

But this thought-provoking psychological thriller also raises fundamental and felicitous ethical questions about extending life beyond its natural boundaries. Postulating the moral and ethical issues that surround mortality have long been defining characteristics of many notable stories within the sci-fi genre. In fact, the Mary Shelley’s age-old novel, Frankenstein, while having little to no direct plot overlaps [with SELF/LESS], it is considered by many to be among the first examples of the science fiction genre.

Continue reading “Never Say Die – SELF/LESS from Science-Fiction to -Fact” »

Biography : Scott Aaronson is an Associate Professor of Electrical Engineering and Computer Science at MIT. His research interests center around the capabilities and limits of quantum computers, and computational complexity theory more generally. He also has written about consciousness and personal identity and the relevance of quantum mechanics to these issues.

Michael Cerullo: Thanks for taking the time to talk with me. Given the recent advances in brain preservation, questions of personal identity are moving from merely academic to extremely practical questions. I want to focus on your ideas related to the relevance of quantum mechanics to consciousness and personal identity which are found in your paper “Ghost in the Quantum Turing Machine” ( http://arxiv.org/abs/1306.0159 ), your blog “Could a Quantum Computer Have Subjective Experience?” ( http://www.scottaaronson.com/blog/?p=1951 ), and your book “Quantum Computing since Democritus” ( http://www.scottaaronson.com/democritus/) .

Before we get to your own speculations in this field I want to review some of the prior work of Roger Penrose and Stuart Hameroff ( http://www.quantumconsciousness.org/content/hameroff-penrose…-or-theory ). Let me try to summarize some of the criticism of their work (including some of your own critiques of their theory). Penrose and Hameroff abandon conventional wisdom in neuroscience (i.e. that neurons are the essential computational element in the brain) and instead posit that the microtubules (which conventional neuroscience tell us are involved in nucleic and cell division, organization of intracellular structure, and intracellular transport, as well as ciliary and flagellar motility) are an essential part of the computational structure of the brain. Specifically, they claim the microtubules are quantum computers that grant a person the ability to perform non-computable computations (and Penrose claims these kinds of computations are necessary for things like mathematical understanding). The main critiques of their theory are: it relies on future results in quantum gravity that don’t exist; there is no empirical evidence that microtubules are relevant to the function of the brain; work in quantum decoherence also makes it extremely unlikely that the brain is a quatum computer; even if a brain could somehow compute non-computable functions it isn’t clear what this has to do with consciousness. Would you say these are fair criticisms of their theory and are there any other criticisms you see as relevant?

Continue reading “Scott Aaronson On The Relevance Of Quantum Mechanics To Brain Preservation, Uploading, And Identity” »

Cannot wait to hear Mckenna’s perspective on BMIs for brain connection to all things digital, and microbots used to extend life as well as bionic body parts.

Famed psychonaut Terence Mckenna envisioned a very radical approach of bridging psychedelics with virtual reality to create a supercharged version of consciousness in which language, or rather the meaning behind what we speak, could be made visual in front of our very eyes.

In Mckenna’s “cyberdelic” future of virtual reality, artists and the revival of art, would be at the forefront of innovation, according to a talk he gave to a German audience in 1991.

Continue reading “Terence Mckenna’s ‘cyberdelic’ predictions for Virtual Reality 25 years on” »

http://www.transcendencemovie.com/

Dr. Will Caster: “For 130,000 years, our capacity for reason has remained unchanged. The combined intellect of the neuroscientists, engineers, mathematicians and hackers in this auditorium pales in comparison to even the most basic AI. Once online, a sentient machine will quickly overcome the limits of biology. And in a short time, its analytical power will be greater than the collective intelligence of every person born in the history of the world. So now imagine such an entity with the full range of human emotion. Even self-awareness. Some scientists refer to this as ‘the Singularity’. I call it ’Transcendence’. The path to building such a super-intelligence requires us to unlock the most fundamental secrets of the universe. What is the nature of consciousness? Is there a soul? And if so, where does it reside?”

Luddite: “Dr. Caster.”

Continue reading “‘Some scientists refer to this as the Singularity. I call it Transcendence.’” »

Controlling the brain, consciousness and the unconscious through artificial means has long been a staple plot of science fiction. Yet history has a way of proving the fictional to end up as possible, and the future of brain-machine interface appears to hold greater promise than ever before.

Image Credit: Society for Neuroscience (SFN)

According to Neuroscience Researcher, Yale University Fellow, and the Director of Yale’s Clinical Neuroscience Imaging Center, Dr. Hal Blumenfeld, we can now therapeutically (and safely) go inside the brain. As he reflected on the recent advances in neuroscience, Blumenfeld cited the progress that’s been made in the last decade in understanding the relationship between brain activity and conscious thought as one of the biggest breakthroughs. The ability to find the switch in the brain that regulates consciousness, and turn it on and off, is a major step toward the treatment of epilepsy, brain injuries and more, and could have a profound effect on mankind, he said.

“I think the exciting advances are really looking in the network approach to understanding the brain, looking at the brain as a network, and understanding that, for something as wide reaching as consciousness to happen, you really need the whole brain network or most of the brain,” Blumenfeld said. “There’s a switch deep in the middle of the brain that can either be turned on or off. When that gets turned on, the whole rest of the brain network, including the cortex, all start to interact and create consciousness. When that switch gets flipped off, consciousness is turned down and we lose consciousness.”

Continue reading “Unlocking the Brain a Healing Promise for Those Who Suffer” »

Optogenetic laser light stimulation of the thalamus (credit: Jia Liu et al./eLife)

By flashing high-frequency (40 to 100 pulses per second) optogenetic lasers at the brain’s thalamus, scientists were able to wake up sleeping rats and cause widespread brain activity. In contrast, flashing the laser at 10 pulses per second suppressed the activity of the brain’s sensory cortex and caused rats to enter a seizure-like state of unconsciousness.

“We hope to use this knowledge to develop better treatments for brain injuries and other neurological disorders,” said Jin Hyung Lee, Ph.D., assistant professor of neurology, neurosurgery, and bioengineering at Stanford University, and a senior author of the study, published in the open-access journal eLIFE.

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Are we evolving into new species with hybrid thinking interlinked into the Global Mind? At what point will the Web may become self-aware? Or is it already? Once our neocortices are seamlessly connected to the Web, how will that feel like to step up one level above human consciousness to global consciousness?

In his book “The Global Brain” Howard Bloom argues that humans are a lot like neurons of the “global connectome”, and the coming Internet of Things (IoT) with trillions of sensors around the planet will become effectively the nervous system of Earth.

According to Gaia hypothesis by James Lovelock, we have always been an integral part of this “Meta-Mind”, collective consciousness, global adaptive and self-regulating system while tapping into vast resources of information pooling and at the same time having a “shared hallucination”, we call reality.

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