Lifeboat Foundation

You get out what you put in.

You are what you eat, the old saying goes, but why is that so? Researchers have known for some time that diet affects the balance of microbes in our bodies, but how that translates into an effect on the host has not been understood. Now, research in mice is showing that microbes communicate with their hosts by sending out metabolites that act on histones—thus influencing gene transcription not only in the colon but also in tissues in other parts of the body. The findings publish November 23 in Molecular Cell.

“This is the first of what we hope is a long, fruitful set of studies to understand the connection between the microbiome in the gut and its influence on host health,” says John Denu, a professor of biomolecular chemistry at the University of Wisconsin, Madison, and one of the study’s senior authors. “We wanted to look at whether the gut microbiota affect epigenetic programming in a variety of different tissues in the host.” These tissues were in the proximal colon, the liver, and fat tissue.

Continue reading “Changes in the diet affect epigenetics via the microbiota” »

29th November in Berlin there is a meetup for LE enthusiasts.

Announcing our year-end meetup in Berlin.

Join our casual get together of like-minded people. We chat about extending our healthy lifespans and the latest developments in this exciting field.

Continue reading “Life Extension Meetup” »

One of the biggest puzzles in physics is that eighty-five percent of the matter in our universe is “dark”: it does not interact with the photons of the conventional electromagnetic force and is therefore invisible to our eyes and telescopes. Although the composition and origin of dark matter are a mystery, we know it exists because astronomers observe its gravitational pull on ordinary visible matter such as stars and galaxies.

Some theories suggest that, in addition to gravity, dark matter particles could interact with visible matter through a new force, which has so far escaped detection. Just as the electromagnetic force is carried by the photon, this dark force is thought to be transmitted by a particle called “dark” photon which is predicted to act as a mediator between visible and dark matter.

“To use a metaphor, an otherwise impossible dialogue between two people not speaking the same language (visible and dark matter) can be enabled by a mediator (the dark photon), who understands one language and speaks the other one,” explains Sergei Gninenko, spokesperson for the NA64 collaboration.

Destroying and replacing the immune system is one of the approaches to treat the aging process.

Fightaging! provides some commentary about the immune system in relation to aging. Addressing the decline of the immune system is one of the approaches SRF is interested in and is a cornerstone of rejuvenation biotechnology.

“Understanding exactly how aging progressively harms the intricate choreography of the immune response is a massive project, and nowhere near completion. It is possible to judge how far along researchers are in this work by the side effect of the quality of therapies for autoimmune disease, which are malfunctions in immune configuration, and largely incurable at the present time. From a practical point of view, and as mentioned above, the best prospects for effective treatments in the near future involve destroying and recreating the immune system. That works around our comparative ignorance by removing all of the problems that researchers don’t understand in addition to ones that they do.”

Continue reading “Some Adaptive Immune Cells Become More Innate-Like in the Aged Immune System” »

This gives a very simple summary of the process of drug development.

The development process from Pre-Clinical testing to an approved product we can use is a long one. A global average of 17 years with the US being 12 years is the historical norm for new drugs and therapies to be developed.

#aging #crowdfundthecure

Continue reading “The road is long but we can get there” »

A laboratory in Lanarkshire has started harvesting stem cells from children’s teeth.

It’s hoped the cells can be used in a cure if the children develop a disease later in life.

The American company BioEden will cryogenically store the cells in return for a monthly fee.

Continue reading “Commercial harvesting of stem cells under way” »

We took the technology out of the studio and into a car – making Holoportation truly mobile. To accomplish this, we reduced the bandwidth requirements by 97%, while still maintaining quality. This new mobile Holoportation system greatly increases the potential applications of real-time 3D capture and transmission.

Scientists have managed to coax living cells into making carbon-silicon bonds, demonstrating for the first time that nature can incorporate silicon — one of the most abundant elements on Earth — into the building blocks of life.

While chemists have achieved carbon-silicon bonds before — they’re found in everything from paints and semiconductors to computer and TV screens — they’ve so far never been found in nature, and these new cells could help us understand more about the possibility of silicon-based life elsewhere in the Universe.

After oxygen, silicon is the second most abundant element in Earth’s crust, and yet it has nothing to do with biological life.

Continue reading “For the First Time, Living Cells Have Formed Carbon-Silicon Bonds” »

In Brief:

• IBM surveyed 200 global banks and financial institutions as part of two recently released studies.
• The widespread use of Blockchain could lead to more secure, efficient banking experiences.

Recent reports by IBM have revealed that by 2017, 15 percent of big banks worldwide and 14 percent of major financial institutions will be using Blockchain technology.