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The current standard of care for psychosis is a diagnostic interview, but what if it could be diagnosed before the first symptom emerged? Researchers at the Del Monte Institute for Neuroscience at the University of Rochester are pointing toward a potential biomarker in the brain that could lead to more timely interventions and personalized care.

“Establishing such biomarkers could provide a key step in changing how we care for, treat, and offer interventions to people with ,” said Brian Keane, Ph.D., assistant professor of Psychiatry, Center for Visual Science, and Neuroscience at the University of Rochester Medical Center.

Keane recently co-authored an article in Molecular Psychiatry that identifies how MRI scans could reveal in people with psychosis.

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When water freezes slowly, the location where water turns into ice—known as the freezing front—forms a straight line. Researchers from the University of Twente showed how droplets that interact with such a freezing front cause surprising deformations of this front. These new insights were published in Physical Review Letters and show potential for applications in cryopreservation and food engineering techniques.

When water freezes, it is often thought of as a predictable, solid block forming layer by layer. But what happens if the progressing freezing front encounters or ? Researchers from the University of Twente have explored this question, discovering that droplets can cause surprising deformations in the way ice forms.

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Using the European XFEL free-electron laser, researchers demonstrate terawatt-scale, attosecond hard X-ray pulses. Ten pulse trains per second, each containing hundreds of pulses at megahertz repetition rates, are achieved. Such short and intense pulses at high repetition rate enable unprecedented damage-free X-ray measurements with attosecond temporal resolution.

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In a chilling Italian lab, scientists utilize extreme cold and ancient materials to challenge existing physics laws.

Their research, aiming to detect phenomena like neutrinoless double beta decay, could redefine understanding of matter and antimatter in the universe, involving students in groundbreaking experiments.

Exploring the universe’s mysteries: the italian lab.

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Neuroscience aficionados may enjoy my preprint that compares leading imaging technologies for whole-brain mammalian connectomics, now with major updates/improvements: Link: arxiv.org/abs/2405.

Mammalian whole-brain connectomes at nanoscale synaptic resolution are a crucial ingredient for holistic understanding of brain function. Imaging these connectomes at sufficient resolution to densely reconstruct cellular morphology and synapses represents a longstanding goal in neuroscience. Although the technologies needed to reconstruct whole-brain connectomes have not yet reached full maturity, they are advancing rapidly enough that the mouse brain might be within reach in the near future. Detailed exploration of these technologies is warranted to help plan projects with varying goals and requirements. Whole-brain human connectomes remain a more distant goal yet are worthy of consideration to orient large-scale neuroscience program plans. Here, we quantitatively compare existing and emerging imaging technologies that have potential to enable whole-brain mammalian connectomics.

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In 2019, the High Energy Density Science (HEDS) Center at Lawrence Livermore National Laboratory (LLNL) launched its postdoctoral fellowship program, welcoming one new scientist annually to come and conduct research for a two-year term. Supported by LLNL’s Weapons Physics and Design program, HEDS fellows are encouraged to pursue their own research agenda as it relates to the study of matter and energy under extreme conditions.

The most recent postdoctoral fellows, physicist Elizabeth “Liz” Grace (2022 fellow) and plasma physicist Graeme Sutcliffe (2023 fellow), are using high-intensity lasers and advanced diagnostics to observe the behaviors of plasma. A plasma, known as the “fourth state of matter,” is a superheated, ionized gas that makes up the majority of visible matter in the universe, like stars and nebulae. Replicating these conditions is a key step to achieving robust igniting inertial fusion designs for energy resilience.

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From brain implants that allow paralyzed patients to communicate to the wearable devices enhancing our capabilities, brain-computer interfaces could change the way we use our minds forever.

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Continue reading “The Thrill and Threat of Mind Hacking | Posthuman with Emily Chang” | >