Lifeboat Foundation: Safeguarding Humanity
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This is important because “the go-to treatment for many cases of depression is medication…this treatment option can cause as many issues as the problem it is trying to solve. Antidepressants can put residents at greater risk of falls, negative health complications and other poor conditions…studies indicate that antidepressants may not be effective for most older Americans. (Additionally) Medication adherence is another significant challenge.”

___ Why technology — not medication — is the future of treating older adults with depression (McKnight’s Long-term Care News): “The go-to treatment for many cases of depression is medication. Unfortunately, this treatment option can cause as many issues as the problem it is trying to solve. Antidepressants can put.

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DALLAS – March 29, 2018 – Researchers from UT Southwestern’s Charles and Jane Pak Center for Mineral Metabolism and Clinical Research and Internal Medicine’s Division of Nephrology recently published work in Nature that reveals the molecular structure of the so-called “anti-aging” protein alpha Klotho (a-Klotho) and how it transmits a hormonal signal that controls a variety of biologic processes. The investigation was performed in collaboration with scientists from New York University School of Medicine and Wenzhou Medical University in China.

Studies at UTSW two decades ago by Dr. Makoto Kuro-o, Professor of Pathology, demonstrated that mice lacking either a-Klotho or the hormone FGF23 suffered from premature and multiple organ failure as well as other conditions, including early onset cardiovascular disease, cancer, and cognitive decline. Because defects in a-Klotho lead to symptoms seen in aging, researchers inferred that a-Klotho suppresses aging, leading to great interest in how the a-Klotho protein might work together with the hormone FGF23 to fulfill their roles.

A-Klotho can exist on the surface of a cell or can be released from the cell and circulate in body fluids, including the blood, as soluble a-Klotho. The cell-attached form and the circulating form of a-Klotho were previously and universally believed to serve completely different functions.

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WASHINGTON — The U.S. military got is first big taste of artificial intelligence with Project Maven. An Air Force initiative, it began more than a year ago as an experiment using machine learning algorithms developed by Google to analyze full-motion video surveillance.

The project has received high praise within military circles for giving operators in the field instant access to the type of intelligence that typically would have taken a long time for geospatial data analysts to produce.

Project Maven has whetted the military’s appetite for artificial intelligence tools. And this is creating pressure on the National Geospatial-Intelligence Agency to jump on the AI bandwagon and start delivering Maven-like products and services.

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And inflammation is one of the three primary ageing processes.

Scientists have discovered a new metabolic process in the body that can switch off inflammation. They have discovered that ‘itaconate’—a molecule derived from glucose—acts as a powerful off-switch for macrophages, which are the cells in the immune system that lie at the heart of many inflammatory diseases including arthritis, inflammatory bowel disease and heart disease.

The scientists, working in the School of Biochemistry and Immunology in the Trinity Biomedical Sciences Institute at Trinity College Dublin, hope their discovery will have relevance for inflammatory and infectious diseases—and that their findings may also help to develop much-needed new drugs to treat people living with these conditions.

Professor of Biochemistry at Trinity, Luke O’Neill, was, along with Dr. Mike Murphy of the University of Cambridge, the joint leader of the work just published in leading international journal Nature. The discoveries were made using both human cells and mice as a model organism.

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