Researchers at Purdue University, Indiana, have developed a method to transform ordinary clothes into battery-free wearables that are waterproof and resistant to laundry. These smart fabrics can be powered wirelessly through a flexible, silk-based coil sewn on the textile.
Using a mouse model, Chen and the team delivered a viral construct containing TRPV1 ion channels to genetically-selected neurons. Then, they delivered small burst of heat via low-intensity focused ultrasound to the select neurons in the brain via a wearable device. The heat, only a few degrees warmer than body temperature, activated the TRPV1 ion channel, which acted as a switch to turn the neurons on or off.
Neurological disorders such as Parkinson’s disease and epilepsy have had some treatment success with deep brain stimulation, but those require surgical device implantation. A multidisciplinary team at Washington University in St. Louis has developed a new brain stimulation technique using focused ultrasound that is able to turn specific types of neurons in the brain on and off and precisely control motor activity without surgical device implantation.
The team, led by Hong Chen, assistant professor of biomedical engineering in the McKelvey School of Engineering and of radiation oncology at the School of Medicine, is the first to provide direct evidence showing noninvasive, cell-type-specific activation of neurons in the brain of mammal by combining ultrasound-induced heating effect and genetics, which they have named sonothermogenetics. It is also the first work to show that the ultrasound-genetics combination can robustly control behavior by stimulating a specific target deep in the brain.
The company wants to develop new human-computer interactions. Will we be able to trust it with a new form of personal data?
Famed longevity pioneer Aubrey de Grey, Chief Science Officer of SENS Research Foundation, joins Geoffrey Woo, Founder and Chairman of Health Via Modern Nutrition Inc., for an enlightening conversation about advances in longevity, the investments and technologies that extend life, and the challenges and opportunities of a world in which people live longer. He walks us through his damage repair therapies with a focus on rejuvenation, prevention, and wearable technologies. Filmed on May 17, 2021. To continue the discussion with fellow Real Vision members on this interview, click here to visit the Exchange: https://rvtv.io/2T7nqZL
Key Learnings: Longevity escape velocity, which is a term de Grey coined, is the idea in which life expectancy is extended longer than the time that is passing, and he estimates a 50% chance that aging could be brought under medical control in as little as 15 years’ time. To learn more about SENS’ research and advancements, please visit their site here: https://www.sens.org/.
CES 2021 is blowing up with a lot of announcements despite being a virtual event. Among the lot, a Japanese Startup now says that its wearable can help you monitor Blood Glucose without piercing your skin.
Quantum Operation Inc., has showcased a prototype of a Wearable that typically is like a Smartwatch. It says that the wearable can measure and monitor the Glucose levels in Blood precisely in addition to heart rate and ECG. Apparently, this is possible due to the presence of a Spectrometer inside.
Scientists at Osaka University, in cooperation with Joanneum Research (Weiz, Austria), have developed wireless health monitoring patches that use embedded piezoelectric nanogenerators to power themselves with harvested biomechanical energy. This work may lead to new autonomous health sensors as well as battery-free wearable electronic devices.
As wearable technology and smart sensors become increasingly popular, the problem of providing power to all of these devices become more relevant. While the energy requirements of each component may be modest, the need for wires or even batteries become burdensome and inconvenient. That is why new energy harvesting methods are needed. Also, the ability for integrated health monitors to use ambient motion to both power and activate sensors will help accelerate their adoption in doctor’s offices.
Now, an international team of researchers from Japan and Austria has invented new ultraflexible patches with a ferroelectric polymer that can not only sense a patient’s pulse and blood pressure, but also power themselves from normal movements. The key was starting with a substrate just one micron thick. Using a strong electric field, ferroelectric crystalline domains in a copolymer were aligned so that the sample had a large electric dipole moment. Based on the piezoelectric effect, which is very efficient in converting natural motion into small electric voltages, the device responds rapidly to strain or pressure changes. These voltages can be transduced either into signals for the medical sensors or to directly harvest the energy. “Our e-health patches may be employed as part of screening for lifestyle-related diseases such as heart disorders, signs of stress, and sleep apnea,” first-author Andreas Petritz says.
**Engineers, using artificial intelligence and wearable cameras, now aim to help robotic exoskeletons walk by themselves.**
Increasingly, researchers around the world are developing lower-body exoskeletons to help people walk. These are essentially walking robots users can strap to their legs to help them move.
One problem with such exoskeletons: They often depend on manual controls to switch from one mode of locomotion to another, such as from sitting to standing, or standing to walking, or walking on the ground to walking up or down stairs. Relying on joysticks or smartphone apps every time you want to switch the way you want to move can prove awkward and mentally taxing, says Brokoslaw Laschowski, a robotics researcher at the University of Waterloo in Canada.
The more data collected, the better the results.
Understanding the genetics of complex diseases, especially those related to the genetic differences among ethnic groups, is essentially a big data problem. And researchers need more data.
1000, 000 genomes
To address the need for more data, the National Institutes of Health has started a program called All of Us. The project aims to collect genetic information, medical records and health habits from surveys and wearables of more than a million people in the U.S. over the course of 10 years. It also has a goal of gathering more data from underrepresented minority groups to facilitate the study of health disparities. The All of Us project opened to public enrollment in 2018, and more than 270000 people have contributed samples since. The project is continuing to recruit participants from all 50 states. Participating in this effort are many academic laboratories and private companies.
One wearable emerged victorious over the others in each of the three categories. I’m including the runners-up for context and to provide an alternative if you’re not convinced by my top pick.
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I came to the human life extension community not as a spanner (initially), biohacker, or a young person filled with existential dread, but as a person obsessed with quantified self. As a teen, I used pencil and paper to track my sleep and my food intake. As a college student, I wore a pedometer and tracked my daily steps on a spreadsheet. In 2014, Fitbit released the Fitbit Force, and since then I’ve had some version of top wearable on my wrist, continuously tracking what I do.
The feedback I’ve gotten from these devices is exceptional. I know that I gain, on average, 1.7 pounds before every menstrual cycle, and that I lose that weight about a day before it’s finished. I know that I need about seven hours and 40 minutes of sleep every night to feel well-rested. I know that if I get at least 40 minutes of cardio on one day, the following day my resting heart rate is a beat or two lower than my overall average. Knowing my body this well puts me in a great place to know if something is going wrong, if I need to reconfigure my lifestyle to push my metrics in the right direction.
From microwave ovens to Wi-Fi connections, the radio waves that permeate the environment are not just signals of energy consumed but are also sources of energy themselves. An international team of researchers, led by Huanyu “Larry” Cheng, Dorothy Quiggle Career Development Professor in the Penn State Department of Engineering Science and Mechanics, has developed a way to harvest energy from radio waves to power wearable devices.
The researchers recently published their method in Materials Today Physics.
According to Cheng, current energy sources for wearable health-monitoring devices have their place in powering sensor devices, but each has its setbacks. Solar power, for example, can only harvest energy when exposed to the sun. A self-powered triboelectric device can only harvest energy when the body is in motion.
