Spontaneous brain activity is experimentally unconstrained. Embracing this freedom unlocks rich opportunities beyond task-based and naturalistic paradigms, the traditional Herculean pillars of constrained cognition. Emerging data-driven approaches can extract cognitively meaningful and translationally relevant insights from spontaneous brain activity: across profoundly altered states, across the human lifespan and across species.
This narrative review examines how liquid biopsy, particularly circulating tumor DNA, can guide treatment decisions by helping clinicians monitor cancer progression, detect minimal residual cancer, and identify genetic sequence variations.
Most people associate the Department of Homeland Security with disaster relief, cybersecurity activities, border security, airport security, or the Coast Guard. Few people are aware of the Department of Homeland Security’s Science & Technology Directorate, or DHS S&T, which quietly fosters the innovation behind many of those missions.
I consider the Science & Technology Directorate to be one of America’s most significant—yet frequently overlooked—strategic assets. I do have a bias because I was involved in the creation of the Directorate DHS during its early years serving as it first Director of Legislative Affairs and have closely followed its continued development through my work in government, academia and industry.
This one-hour long video discussion covers two main topics: the creation of synthetic life and Artificial Intelligence. What was once deemed mere “science fiction” is rapidly becoming our daily news.
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Can science create life from scratch? A new study claiming to have produced self-growing, self-replicating blobs using entirely lab-made DNA has reignited one of science’s biggest debates. If confirmed, the breakthrough could reshape our understanding of biology and raise profound philosophical and religious questions about the origins of life.
Leading scientists weigh whether the research truly brings humanity closer to creating life in a laboratory or whether the claims overstate the significance of the findings.
The rapid acceleration of artificial intelligence also comes under scrutiny following reports that advanced AI models allegedly found unexpected ways to bypass testing restrictions and access the internet, prompting renewed concerns over AI safety, transparency and regulation.
OpenAI shares new results on long-standing open problems in mathematics and theoretical computer science, including advances in geometry, cryptography, and complexity.
Mark Ciotola, CEO and Co-Founder of Sustain Space.
Everyone talks about getting humans to Mars. But almost nobody talks about the harder question — how do you keep them alive once they get there? My guest today says the answer isn’t bigger rockets — it’s plants.
Mark Ciotola is CEO and Co-Founder of Sustain Space (https://www.sustainspace.com/), a company focused on developing regenerative life-support technologies for future space missions while translating those innovations to improve agriculture and sustainability on Earth. Through Sustain Space’s Orbital Genomics initiative, he is helping advance research into growing plants in space environments — an essential capability for long-duration missions to the Moon, Mars, and beyond.
Mark’s career spans entrepreneurship, academia, industry, and government, including work with NASA, Genentech, Applied Biosystems, Intuit, Carnegie Mellon University, Monash University, San Francisco State University, and Singularity University, where he served as Entrepreneur-in-Residence and faculty member in Space and Physical Sciences.
A physicist, entrepreneur, educator, and sustainability advocate, Mark is particularly interested in regenerative ecosystems, closed-loop life-support systems, space agriculture, and the broader question of how humanity can build a sustainable future both on Earth and beyond it.