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Nice paper on Neural Circuit structures.


Plasticity between neural connections plays a key role in our ability to process and store information. One of the fundamental questions on plasticity, is the extent to which local processes, affecting individual synapses, are responsible for large scale structures of neural connectivity. Here we focus on two types of structures: synfire chains and self connected assemblies. These structures are often proposed as forms of neural connectivity that can support brain functions such as memory and generation of motor activity. We show that an important plasticity mechanism, spike timing dependent plasticity, can lead to autonomous emergence of these large scale structures in the brain: in contrast to previous theoretical proposals, we show that the emergence can occur autonomously even if instructive signals are not fed into the neural network while its form is shaped by synaptic plasticity.

Citation: Ravid Tannenbaum N, Burak Y (2016) Shaping Neural Circuits by High Order Synaptic Interactions. PLoS Comput Biol 12: e1005056. doi:10.1371/journal.pcbi.1005056

Editor: Peter E. Latham, UCL, UNITED KINGDOM

WILLIAMSBURG, Va.: The Pentagon’s top weapons buyer, Frank Kendall, warned today that the US might hobble itself in future warfare by insisting on human control of thinking weapons if our adversaries just let their robots pull the trigger. Kendall even worries that Deputy Defense Secretary Bob Work is being too optimistic when Work says humans and machines working together will beat robots without oversight.

These are unnerving ideas — and top Army leaders swiftly responded with concern that robots would shoot civilians if you take the human out of the loop. This is what Vice Chairman of the Joint Chiefs Paul Selva calls the Terminator Conundrum: “When do we want to cross that line as humans? And who wants to cross it first? Those are really hard ethical questions.” They are also a fundamental question of combat effectiveness.

“Even in a more conventional conflict, we’re quite careful about not killing innocent civilians,” said Kendall. “I don’t expect our adversaries to all behave that way, and the advantage you have if you don’t worry about that as much, is you make decisions more quickly” — which can spell the difference between victory and defeat.

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Leading AI scientist Ben Goertzel says, “In the future, an AI will tutor your children and take care of your grandma. It won’t be Terminator robots marching down the street.” Watch Episode 2 of “Future First” with Popular Science.

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My exclusive interview with Libertarian presidential candidate Gary Johnson on some hard science & tech issues, including transhumanism, longevity, AI, and gene editing. This is also my first story for Futurism. For the record, I am trying, along with millions of others, to get Gary Johnson into the Presidentia l debates! No matter who you plan to vote for, it would be good for America to have him in the debates so a third voice is heard:


Libertarian Presidentia l candidate Gary Johnson wants humans to live a lot longer and isn’t worried about AI becoming the Terminator. Here, Futurist Zoltan Istvan gains an exclusive interview with Johnson, who is polling double digits nationally and hopes to be in the Presidentia l debates with Trump and Clinton in October.

Disclaimer: The views and opinions expressed are solely those of the author. They do not necessarily represent the views of Futurism or its affiliates.

I recently sat down with Libertarian Presidentia l candidate Gary Johnson at his home in New Mexico and watched an episode of Orphan Black, the hit sci-fi show. Between his CNN Town Hall meetings and endless speeches on the campaign trail, you’re probably asking: How did Gary get the time to watch a television show? It’s a good question, but the former Governor made the time, because he’s interested in the future and willing to explore how it might unfold.

Ford says it’s going to deliver self-driving cars by 2021 – and these will ship in volume, and will also lack steering wheels, brake or gas pedals, offering full Level 4 self-driving features which don’t require a human driver at all, the company announced at a press conference in Palo Alto today.

The car maker says that it has held off making any announcements about when to deliver self-driving vehicles until now because it isn’t in a race to make announcements. But it did say it is making self-driving vehicle deployment a priority, because of the advantages it offers in terms of customer experience and passenger safety.

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Researchers from Polytechnique Montréal, Université de Montréal and McGill University have just achieved a spectacular breakthrough in cancer research. They have developed new nanorobotic agents capable of navigating through the bloodstream to administer a drug with precision by specifically targeting the active cancerous cells of tumours. This way of injecting medication ensures the optimal targeting of a tumour and avoids jeopardizing the integrity of organs and surrounding healthy tissues. As a result, the drug dosage that is highly toxic for the human organism could be significantly reduced.

This scientific breakthrough has just been published in the prestigious journal Nature Nanotechnology in an article titled “Magneto-aerotactic bacteria deliver drug-containing nanoliposomes to tumour hypoxic regions.” The article notes the results of the research done on mice, which were successfully administered nanorobotic agents into colorectal tumours.

“These legions of nanorobotic agents were actually composed of more than 100 million flagellated bacteria — and therefore self-propelled — and loaded with drugs that moved by taking the most direct path between the drug’s injection point and the area of the body to cure,” explains Professor Sylvain Martel, holder of the Canada Research Chair in Medical Nanorobotics and Director of the Polytechnique Montréal Nanorobotics Laboratory, who heads the research team’s work. “The drug’s propelling force was enough to travel efficiently and enter deep inside the tumours.”

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