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A Single Cubic Millimeter of Brain Tissue May Have Just Changed Neuroscience Forever

Scientists have mapped an unprecedentedly large portion of the brain of a mouse. The cubic millimeter worth of brain tissue represents the largest piece of a brain we’ve ever understood to this degree, and the researchers behind this project say that the mouse brain is similar enough to the human brain that they can even extrapolate things about us. A cubic millimeter sounds tiny—to us, it is tiny—but a map of 200,000 brain cells represents just over a quarter of a percent of the mouse brain. In brain science terms, that’s extraordinarily high. A proportionate sample of the human brain would be 240 million cells.

Within the sciences, coding and computer science can sometimes overshadow the physical and life sciences. Rhetoric about artificial intelligence has raced ahead with terms like “human intelligence,” but the human brain is not well enough understood to truly give credence to that idea. Scientists have worked for decades to analyze the brain, and they’re making great progress despite the outsized rhetoric working against them.

ODEP-Based Robotic System for Micromanipulation and In-Flow Analysis of Primary Cells

The presence of cellular defects of multifactorial nature can be hard to characterize accurately and early due to the complex interplay of genetic, environmental, and lifestyle factors. With this study, by bridging optically-induced dielectrophoresis (ODEP), microfluidics, live-cell imaging, and machine learning, we provide the ground for devising a robotic micromanipulation and analysis system for single-cell phenotyping. Cells under the influence of nonuniform electric fields generated via ODEP can be recorded and measured. The induced responses obtained under time-variant ODEP stimulation reflect the cells’ chemical, morphological, and structural characteristics in an automated, flexible, and label-free manner.

New chip tests cooling solutions for stacked microelectronics

As demand grows for more powerful and efficient microelectronics systems, industry is turning to 3D integration—stacking chips on top of each other. This vertically layered architecture could allow high-performance processors, like those used for artificial intelligence, to be packaged closely with other highly specialized chips for communication or imaging. But technologists everywhere face a major challenge: how to prevent these stacks from overheating.

Now, MIT Lincoln Laboratory has developed a specialized chip to test and validate cooling solutions for packaged chip stacks. The chip dissipates extremely , mimicking high-performance logic chips, to generate heat through the silicon layer and in localized . Then, as cooling technologies are applied to the packaged stack, the chip measures temperature changes. When sandwiched in a stack, the chip will allow researchers to study how heat moves through stack layers and benchmark progress in keeping them cool.

“If you have just a , you can cool it from above or below. But if you start stacking several chips on top of each other, the heat has nowhere to escape. No cooling methods exist today that allow industry to stack multiples of these really high-performance chips,” says Chenson Chen, who led the development of the chip with Ryan Keech, both of the laboratory’s Advanced Materials and Microsystems Group.

Ray Kurzweil’s 7 Boldest Predictions—What’s Still on Track?

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Ray Kurzweil, one of the world’s leading futurists, has made hundreds of predictions about technology’s future. From portable devices and wireless internet to brain-computer interfaces and nanobots in our bloodstream, Kurzweil has envisioned a future that sometimes feels like science fiction—but much of it is becoming reality.

In this video, we explore 7 of Ray Kurzweil’s boldest predictions:

00:00 — 01:44 Intro.

01:44 — 02:42 Prediction 1: Portable Devices and Wireless Internet.

02:42 — 03:34 Prediction 2: Self-Driving Cars by Early 2020s.

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