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Category: nanotechnology – Page 192

Mitochondrial disorders, nano-medicine drug delivery, and innovative therapeutic interventions — dr. volkmar weissig scd, phd — president, world mitochondria society — professor, midwestern university.

Dr. Volkmar Weissig, Sc. D., Ph.D. is a Tenured Full Professor of Pharmacology, Chair of the Department of Pharmaceutical Sciences, and Co-Director of the Nanomedicine Center of Excellence in Translational Cancer Research, at Midwestern University, Glendale, AZ, USA.

Dr. Weissig received his B.S., M.S. and Ph.D. degrees in Chemistry, and his postdoctoral Sc. D. degree in Biochemistry and Pharmaceutical Biotechnology from the Martin-Luther University in Halle (Germany).

Dr. Weissig completed several years of postdoctoral fellowships at the Cardiology Research Center in Moscow (Russia), at the Academic Department of Medicine at the Royal Free Hospital School of Medicine in London (UK), at the Institute of Organic Chemistry at the Czechoslovakian Academy of Science in Prague (CSFR), at the College of Pharmacy and the College of Medicine at the University of Florida, Gainesville, FL, and at Harvard Medical School and Massachusetts General Hospital in Boston, MA.

Before joining the faculty at Midwestern University, Dr. Weissig was an Assistant Professor of Pharmaceutical Sciences at Northeastern University in Boston, MA.

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Ray Kurzweil — Singularitarian Immortalist, Director of Engineering at Google, famous inventor, author of How to Create a Mind http://GF2045.com/speakers/.

A world-class prolific inventor and leading futurist author, “the restless genius” (Wall Street Journal) points to 2045 for the technological singularity when A.I. will surpass human intelligence in his New York Times best seller The Singularity is Near, Amazon’s #1 book in science and philosophy.

In this video Ray Kurzweil discusses his predictions about radical life extension, singularity, life expansion and the imminence of physical immortality. He invites participants to the second international Global Future 2045 congress (June 2013) http://www.GF2045.com.

“If we have radical life extension only, we would get profoundly bored, we’d have profound existential ennui, running out of things to do, and new ideas, but that’s not what’s going to happen. In addition to radical life extension, we’re going to have radical life expansion, we’re going to have millions of virtual environments to explore, we’re going to literally expand our brains.”

“We’ll be routinely able to change our bodies very quickly, as well as our environments in virtual reality, but it will feel very real. We’ll ultimately be able to do that with real reality too, like self-organizing swarms of nanobots that can link themselves up into a virtual body.” says Ray Kurzweil.

For more information about the GF2045 congress, please visit http://www.GF2045.com

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Quantum technology typically employs qubits (quantum bits) consisting of, for example, single electrons, photons or atoms. A group of TU Delft researchers has now demonstrated the ability to teleport an arbitrary qubit state from a single photon onto an optomechanical device—consisting of a mechanical structure comprising billions of atoms. Their breakthrough research, now published in Nature Photonics, enables real-world applications such as quantum internet repeater nodes while also allowing quantum mechanics itself to be studied in new ways.

Quantum optomechanics

The field of quantum optomechanics uses optical means to control mechanical motion in the quantum regime. The first quantum effects in microscale mechanical devices were demonstrated about ten years ago. Focused efforts have since resulted in entangled states between optomechanical devices as well as demonstrations of an optomechanical quantum memory. Now, the group of Simon Gröblacher, of the Kavli Institute of Nanoscience and the Department of Quantum Nanoscience at Delft University of Technology, in collaboration with researchers from the University of Campinas in Brazil, has shown the first successful teleportation of an arbitrary optical qubit state onto a micromechanical quantum memory.

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The extracellular matrix (ECM) including three-dimensional (3D) network and bioelectricity can profoundly influence cell development, migration, and functional expression. In a new report now published on Science Advances, Tong Li and a research team in chemistry, nanotechnology, bioelectronics and advanced materials in China, developed an electromechanical coupling bio-nanogenerator abbreviated bio-NG inspired by biophysical cues of the extracellular matrix. The device contained highly discrete piezoelectric fibers to generate piezo potential of up to millivolts to provide in situ electrical stimulation for living cells.

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GraphWear, a company pursuing needle-free approaches to glucose monitoring, has closed a $20.5 million Series B round. This Series B round is a vote of confidence by investors in GraphWear’s approach: to monitor key metrics in the body, like glucose, without breaking the skin at all.

GraphWear Technologies was founded in 2015 by Rajatesh Gudibande and Saurabh Radhakrishnan, who had both completed master’s degrees in nanotechnology at the University of Pennsylvania. Specifically, GraphWear is developing a skin-surface-level wearable made of graphene (more on this material later). The sensor is small, about the size of an Apple Watch — but the key piece of technology is actually housed on the bottom. It’s a thin slice of graphene that fits onto the back of the watch, or onto a sticker that can be worn on the abdomen.

This Series B round, says Gudibande, will be focused on helping the company build upon previous validation studies of the wearable, completing a pivotal trial and submitting for FDA clearance. The round was led by Mayfield, with participation from MissionBio Capital, Builders VC and VSC Ventures.

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Nonlinearity induced by a single photon is desirable because it can drive power consumption of optical devices to their fundamental quantum limit, and is demonstrated here at room temperature.

The recent progress in nanotechnology1,2 and single-molecule spectroscopy3–5 paves the way for emergent cost-effective organic quantum optical technologies with potential applications in useful devices operating at ambient conditions. We harness a π-conjugated ladder-type polymer strongly coupled to a microcavity forming hybrid light–matter states, so-called exciton-polaritons, to create exciton-polariton condensates with quantum fluid properties. Obeying Bose statistics, exciton-polaritons exhibit an extreme nonlinearity when undergoing bosonic stimulation6, which we have managed to trigger at the single-photon level, thereby providing an efficient way for all-optical ultrafast control over the macroscopic condensate wavefunction. Here, we utilize stable excitons dressed with high-energy molecular vibrations, allowing for single-photon nonlinear operation at ambient conditions.

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A DNA robot that can walk across biological cell membranes is the first one that can control living cells’ behaviour. The researchers who made the robot hope that it could improve cell-based precision medicine.

A team led by Hong-Hui Wang and Zhou Nie from Hunan University, China, has created a synthetic molecular robot that walks along the outer membrane of biological cells. The robot, powered by an enzyme’s catalytic activity, traverses across receptors that act as stepping stones on the cell surface. With each step, the robot activates a signal pathway that regulates cell migration. Driven by the robot’s movement, the cells can reach speeds of 24 μm/hour.

The researchers write that the DNA robot offers, for the first time, an opportunity to accurately and predictably control the nanoscale operations that power a live cell. They suggest that similar molecular machines that guide cell behaviours could play a role in cell-based therapies and regenerative medicine.

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Circa 2012

Faraday and Dirac constructed magnetic monopoles using the practical and mathematical tools available to them. Now physicists have engineered effective monopoles by combining modern optics with nanotechnology. Part matter and part light, these magnetic monopoles travel at unprecedented speeds.

In classical physics (as every student should know) there are no sources or sinks of magnetic field, and hence no magnetic monopoles. Even so, a tight bundle of magnetic flux — such as that created by a long string of magnetic dipoles — has an apparent source or sink at its end. If we map the lines of force with a plotting compass, we think we see a magnetic monopole as our compass cannot enter the region of dense flux. In 1,821 Michael Faraday constructed an effective monopole of this sort by floating a long thin bar magnet upright in a bowl of mercury, with the lower end tethered and the upper end free to move like a monopole in the horizontal plane.

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