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Category: innovation – Page 32

COPENHAGEN, Denmark — In the never-ending quest to unlock the secrets of a long and healthy life, researchers at the University of Copenhagen have made a remarkable discovery. Their study has identified a specific gene that plays a crucial role in extending longevity across various species, including humans.

Publishing their work in the journal Cell Reports, researchers say the gene in question is called OSER1, and it encodes a protein that the team has dubbed a “novel pro-longevity factor.”

“We identified this protein that can extend longevity. It is a novel pro-longevity factor, and it is a protein that exists in various animals, such as fruit flies, nematodes, silkworms, and in humans,” says Professor Lene Juel Rasmussen, the senior author behind the study, in a media release.

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Scientists have grown blood stem cells in the laboratory for the first time in a move that could potentially end the need for stem cell transplants.

During a stem cell (or bone marrow) transplant, damaged blood cells are replaced with healthy ones and can be used to treat conditions such as leukaemia.

However, finding a donor match can be difficult and some patients die before a donor is found.

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Researchers have developed a new magnet-based memory device using helical magnets, promising high-density, non-volatile storage without magnetic field crosstalk.

This breakthrough offers a sustainable solution to current challenges in information storage, with potential for large-scale integration and high durability.

A team of scientists has proposed a new concept for magnet-based memory devices, which might revolutionize information storage devices owing to their potential for large-scale integration, non-volatility, and high durability.

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Summary: Human progress requires a culture of openness to change and innovation, which historically has been rare and resisted by established elites. Periods of remarkable achievement, like that seen in Enlightenment Europe, occurred when societies embraced new ideas and allowed for intellectual and economic freedom. The key to sustained progress lies in maintaining a culture of optimism and a politico-economic system that encourages innovation rather than suppressing it.

To make progress, we must do something differently from what we did yesterday, and we must do it faster, better, or with less effort. To accomplish that, we innovate, and we imitate. That takes a certain openness to surprises, and that openness is rare. It is difficult to come up with something that never existed. It’s also dangerous, since most innovations fail.

If you live close to subsistence level, you don’t have a margin for error. So, if someone wants to hunt in a new way or experiment with a new crop, it is not necessarily popular. There is a reason why most historical societies that came up with a way of sustaining themselves tried to stick to that recipe and considered innovators troublemakers.

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An innovative study of DNA ’s hidden structures may open up new approaches for the treatment and diagnosis of diseases, including cancer.

Researchers at the Garvan Institute have unveiled the first comprehensive map of over 50,000 i-motifs in the human genome, structures distinct from the classic double helix that may play crucial roles in gene regulation and disease. These findings highlight the potential of i-motifs in developing new therapies, particularly in targeting genes associated with cancers.

Unraveling the Mysteries of DNA i-Motifs.

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The Event Horizon Telescope (EHT) Collaboration has enhanced its observational capabilities, achieving unprecedented resolutions by detecting light at a 345 GHz frequency.

This breakthrough allows for detailed imaging of black holes, promising images 50% more detailed than previous ones and the potential to view more black holes than ever before.

Breakthrough in Black Hole Imaging.

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Scientists are working on a “breakthrough” cancer vaccine after discovering how the body’s immune system targets cells devastated by the disease.

A study led by researchers from the University of Southampton found the body’s natural “killer” cells – from the immune system which protects against disease and infections – instinctively recognise and attack a protein that drives cancer growth.

The scientists believe that by using this protein – known as XPO1 – they may be able to activate more killer cells to destroy the disease, paving the way for new and less invasive forms of cancer treatment.

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“DNA, RNA and proteins are the key players to regulate all processes in the cells of our body,” Leiden Professor John van Noort explains. “To understand the (mis-)functioning of these molecules, it is essential to uncover how their 3D structure depends on their sequence and for this it is necessary to measure them one molecule at a time. However, single-molecule measurements are laborious and slow, and the number of possible sequence variations is massive.”

Now the team of scientists developed an innovative tool, called SPARXS (Single-molecule Parallel Analysis for Rapid eXploration of Sequence space), that allows for studying millions of DNA molecules simultaneously.

“Traditional techniques that allow one sequence to be probed at a time usually take hours of measurement time per sequence. With SPARXS, we can measure millions of molecules within a day to a week. Without SPARXS, such a measurement would take several years to decades,” says Delft Professor Chirlmin Joo.

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