U.S. patent officials reexamining claims about who deserves rights to enormously valuable aspect of the invention.
Biochips are essentially tiny laboratories designed to function inside living organisms, and they are driving next-generation DNA sequencing technologies. This powerful combination is capable of solving unique and important biological problems, such as single-cell, rare-cell or rare-molecule analysis, which next-generation sequencing can’t do on its own.
Now that the scaling and throughput power of biochip technologies has emerged, the next trend in biochips will involve being capable of providing applications across a wide spectrum—from identifying rare bacterium to population-based clinical studies.
In APL Bioengineering a group of researchers from Seoul National University explore the role advancements in biochip technology are playing in driving groundbreaking scientific discoveries and breakthroughs in medicine via next-generation sequencing, aka high-throughput sequencing.
The formation of air bubbles in a liquid appears very similar to its inverse process, the formation of liquid droplets from, say, a dripping water faucet. But the physics involved is actually quite different, and while those water droplets are uniform in their size and spacing, bubble formation is typically a much more random process.
Now, a study by researchers at MIT and Princeton University shows that under certain conditions, bubbles can also be coaxed to form spheres as perfectly matched as droplets.
The new findings could have implications for the development of microfluidic devices for biomedical research and for understanding the way natural gas interacts with petroleum in the tiny pore spaces of underground rock formations, the researchers say. The findings are published today in the journal PNAS, in a paper by MIT graduate Amir Pahlavan Ph.D. ‘18, Professor Howard Stone of Princeton, MIT School of Engineering Professor of Teaching Innovation Gareth McKinley, and MIT Professor Ruben Juanes.
In a new survey of the sub-seafloor off the U.S. Northeast coast, scientists have made a surprising discovery: a gigantic aquifer of relatively fresh water trapped in porous sediments lying below the salty ocean. It appears to be the largest such formation yet found in the world. The aquifer stretches from the shore at least from Massachusetts to New Jersey, extending more or less continuously out about 50 miles to the edge of the continental shelf. If found on the surface, it would create a lake covering some 15,000 square miles. The study suggests that such aquifers probably lie off many other coasts worldwide, and could provide desperately needed water for arid areas that are now in danger of running out.
The researchers employed innovative measurements of electromagnetic waves to map the water, which remained invisible to other technologies. “We knew there was fresh water down there in isolated places, but we did not know the extent or geometry,” said lead author Chloe Gustafson, a Ph.D. candidate at Columbia University’s Lamont-Doherty Earth Observatory. “It could turn out to be an important resource in other parts of the world.” The study appears this week in the journal Scientific Reports.
The first hints of the aquifer came in the 1970s, when companies drilled off the coastline for oil, but sometimes instead hit fresh water. Drill holes are just pinpricks in the seafloor, and scientists debated whether the water deposits were just isolated pockets or something bigger. Starting about 20 years ago, study coauthor Kerry Key, now a Lamont-Doherty geophysicist, helped oil companies develop techniques to use electromagnetic imaging of the sub-seafloor to look for oil. More recently, Key decided to see if some form of the technology could also be used also to find fresh-water deposits. In 2015, he and Rob L. Evans of Woods Hole Oceanographic Institution spent 10 days on the Lamont-Doherty research vessel Marcus G. Langseth making measurements off southern New Jersey and the Massachusetts island of Martha’s Vineyard, where scattered drill holes had hit fresh-water-rich sediments.
Over 30 years ago, a molecule with incredible anti-cancer properties was discovered in sea sponges. However, it was so structurally complex scientists have been unable to synthesize it in large enough quantities to be able to test it in humans. Now a team of scientists has finally made a landmark breakthrough, achieving total synthesis of the molecule in volumes large enough to proceed to clinical trials.
A team of researchers from Carnegie Mellon has made a breakthrough in the field of noninvasive robotic device control. Using a noninvasive brain-computer interface, they have developed the first-ever successful mind-controlled robotic arm exhibiting the ability to continuously track and follow a computer cursor.
SpinLaunch has been awarded a responsive launch prototype contract from the DoD, facilitated by DIU for kinetic energy-based launch services.
Media Contact: Diane Murphy ([email protected]) Tel: 310.658.
In a breakthrough that could save thousands of lives, scientists have found a way to convert all blood types to the universal type that is safe for all patients to receive, by using microbes found in the human gut.
Researchers from the University of British Columbia have figured out how to convert blood types A, B and AB into the universal Type O, which all patients can receive in a transfusion, regardless of their own blood type.
Scientists have figured out how to use a laser to transmit audio, ranging from music to speech, to a person across a room without any receiver equipment — a potential breakthrough for the future of audio and communication.
“Our system can be used from some distance away to beam information directly to someone’s ear,” Massachusetts Institute of Technology research Charles M. Wynn said in a press release. “It is the first system that uses lasers that are fully safe for the eyes and skin to localize an audible signal to a particular person in any setting.”
