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Category: health – Page 116

Knowing that you’ve inherited genetic mutations that increase the risk of cancer can help you catch the disease earlier, and if diagnosed, choose the most effective treatments. But despite guidelines that recommend genetic testing for the majority of cancer patients, far too few are tested, according to new research by Stanford Medicine scientists and collaborators.

Among more than a million patients with cancer, only 6.8% underwent germline genetic testing — an analysis of inherited genes — within two years of diagnosis, according to the study published June 5 in the Journal of the American Medical Association. The rates were particularly low among Asian, Black and Hispanic patients.

“When we’re talking about cancer risk, germline genetic testing looks specifically at the genes that, if altered in a way that is harmful, give people a much higher risk of cancer than the average person,” said Allison Kurian, MD, professor of epidemiology and population health, who is the lead author of the study.

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See my explanation of the spent fuel rods and why if something is not done to get water to the spent fuel rod pools at the Zaporizhzhia Nuclear Plant there will be a catastrophic radiation release that may trigger WWIII. See why Russia and Ukraine are each saying the other is going to blow up the cooling pools and the plant. See what that means for you. Take your preps seriously!

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Continue reading “Zaporizhzhia Nuclear Plant a Clear Present Danger” | >

Four individuals have agreed to be sequestered inside a 1,700-square-foot simulated Mars habitat at NASA’s Johnson Space Center to study what it would be like to live on the Red Planet and how humans can learn to cope in that extreme environment.

During their 378-day stay, which officially kicked off earlier this week, they’ll have a surprisingly busy schedule, including a strict exercise regimen as well as a lengthy list of duties, from performing simulated spacewalks to growing crops.

In other words, it’s a demanding job that’s bound to be tough on the crew of four.

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Continue reading “Metabolite Ratios As An Index Of Oxidative Stress” | >

In a significant advance for the treatment of obesity, biotech giant Eli Lilly has announced the results from a trial of retatrutide, which produced a staggering 24.2% weight loss in patients.

Obesity, defined as a body mass index (BMI) of 30 or higher, is a major health issue that has increased significantly over the years. As of today, it affects over 42% of adults in the United States, with 20% of children and adolescents also affected. Worldwide, more than 1 billion people are dealing with the condition, including 650 million adults, 340 million adolescents, and 39 million children.

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Is the Executive Director of the Innovative Genomics Institute (https://innovativegenomics.org/people/brad-ringeisen/), an organization founded by Nobel Prize winner Dr. Jennifer Doudna, on the University of California, Berkeley campus, whose mission is to bridge revolutionary gene editing tool development to affordable and accessible solutions in human health and climate.

Dr. Ringeisen is a physical chemist with a Ph.D. from the University of Wisconsin-Madison, a Bachelor of Science in chemistry from Wake Forest University, a pioneer in the field of live cell printing, and an experienced administrator of scientific research and product development.

Before joining the IGI, Dr. Ringeisen was Director of the Biological Technologies Office at DARPA, where he managed a division working at the cutting edges of biology, physical sciences and engineering. Programs in his office included research in genome editing, epigenetics, neurotechnology, food security and biomanufacturing, as well as diagnostics and therapeutics development.

Prior to DARPA, Dr. Ringeisen ran his own research group at the U.S. Naval Research Laboratory as the head of the Bioenergy and Biofabrication Section where he oversaw diverse research programs including the development and application of laser-assisted printing approaches to biology, development of organs-on-a-chip, microbial energy harvesting and extracellular electron transfer as well as microbial discovery and microbiome characterization.

Continue reading “Dr. Brad Ringeisen, Ph.D. — Executive Director, Innovative Genomics Institute (IGI)” | >

After using the Whisker Litter-Robot 4, I will never return to a regular litter box. The insight it gives me into Norbert’s overall health and the daily cleaning makes it completely worth it. Just be patient with the setup process and with your cat learning a new routine. Norbert’s opinion also upholds the new litter box since he was able to transition pretty seamlessly and gets to have a clean litter box every single time.

Also: This army robot dog is part of a bigger battle for brain-machine interface tech

The Whisker Litter-Robot 4 is no doubt expensive, but the company also offers the previous generation Litter-Robot 3 for a bit cheaper at $549. It’s definitely an investment, but this is a type of automated technology I can get behind.

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The first “AI incident” almost caused global nuclear war. More recent AI-enabled malfunctions, errors, fraud, and scams include deepfakes used to influence politics, bad health information from chatbots, and self-driving vehicles that are endangering pedestrians.

The worst offenders, according to security company Surfshark, are Tesla, Facebook, and OpenAI, with 24.5% of all known AI incidents so far.

In 1983, an automated system in the Soviet Union thought it detected incoming nuclear missiles from the United States, almost leading to global conflict. That’s the first incident in Surfshark’s report (though it’s debatable whether an automated system from the 1980s counts specifically as artificial intelligence). In the most recent incident, the National Eating Disorders Association (NEDA) was forced to shut down Tessa, its chatbot, after Tessa gave dangerous advice to people seeking help for eating disorders. Other recent incidents include a self-driving Tesla failing to notice a pedestrian and then breaking the law by not yielding to a person in a crosswalk, and a Jefferson Parish resident being wrongfully arrested by Louisiana police after a facial recognition system developed by Clearview AI allegedly mistook him for another individual.

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At-Home Metabolomics: https://www.iollo.com?ref=michael-lustgarten.
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NAD+ Quantification: https://www.jinfiniti.com/intracellular-nad-test/

Continue reading “ApoB: Is Lower Always Better?” | >