The site turned out to be 40 times bigger than previously thought.
Category: futurism – Page 74
The specific labeling of RNA in living cells poses many challenges. In a new article published in the journal Nature Chemical Biology, researchers from the University of Innsbruck describe a structure-guided approach to the formation of covalent (i.e., irreversibly tethered) RNA-ligand complexes.
The key to this is the modification of the original ligand with a reactive “handle” that allows it to react with a nucleobase at the RNA binding site. This was first demonstrated in vitro and in vivo using the example of an RNA riboswitch.
The versatility of the approach is highlighted by the first covalent “fluorescent light-up RNA aptamer” (coFLAP). This system retains its strong fluorescence during imaging in living cells even after washing, can be used for high-resolution microscopy and is particularly suitable for FRAP (fluorescence recovery after photobleaching) for monitoring intracellular RNA dynamics.
CISA lists critical flaws in Mitel MiCollab (CVE-2024–41713, CVE-2024–55550) and Oracle WebLogic (CVE-2020–2883).
Two severe vulnerabilities (CVE-2024–9138, CVE-2024–9140) in Moxa routers risk privilege escalation and command execution.
Researchers show they can magnetize an antiferromagnet using terahertz light, switching the state on a million times faster than is possible for other magnetic states.
John Larison’s new novel The Ancients suggests some societies are built for cataclysm.
Chinese state media reported that a 7.1 magnitude earthquake near one of Tibet’s most sacred cities resulted in at least 100 fatalities. The powerful tremor was also felt in neighboring Nepal.
CMOS manufacturing has been harnessed for optical transceivers, and some companies are now looking to build photonic circuits for sensing, quantum science and more.