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DigitalFUTURES / Legends : Denise Scott Brown

28 June 10am EDT/ 4pm CET / 10pm China.

Who are the real legends in architecture? How did they become legends? And what advice might they have to offer the students of today?

This series of interviews brings together some of the leading voices from the world of architecture and beyond. The intention is to record their thoughts for posterity. Videos will be uploaded to the DigitalFUTURES library with subtitles in 12 different languages.

Breast Cancer Spreads More Aggressively at Night, Startling New Study Finds

When people with metastatic breast cancer close their eyes at night, their cancer awakes and starts to spread.

That’s the striking finding from a paper published in Nature this week that overturns the assumption that breast cancer metastasis happens at the same rate around the clock.

The result may change the way that doctors collect blood samples from people with cancer in the future, the researchers say.

A Bile Acid (TBMCA) Is Involved In A Mechanism That Reduces Muscle Mass And Strength

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Papers referenced in the video:
Depletion of gut microbiota induces skeletal muscle atrophy by FXR-FGF15/19 signalling.
https://pubmed.ncbi.nlm.nih.gov/33783283/

Gut microbiota regulates bile acid metabolism by reducing the levels of tauro-beta-muricholic acid, a naturally occurring FXR antagonist.
https://pubmed.ncbi.nlm.nih.gov/23395169/

Fibroblast growth factor 19 regulates skeletal muscle mass and ameliorates muscle wasting in mice.
https://pubmed.ncbi.nlm.nih.gov/28650457/

Irish Archaeologist Identifies Over 3,000-Year-Old Bronze-Age Fortress in Galway Park

An archaeologist in Galway, Ireland, discovered a large Bronze Age fortress on a limestone table, surrounded by seasonal lakes, at Coole Park, Ireland, earlier this week, according to television and radio broadcaster RTÉ. The site was previously known, but its antiquity has been in question until now.

Coole Park, the land on which the fortress sits, is currently a nature preserve. The turloughs, or seasonal lakes, are unique to areas of Ireland west of the River Shannon.

The fortress, dating between 800 and 1,200 BCE, is unique in its use of turloughs, which would have drained and filled with water based on the weather and time of year. These turloughs would have been used strategically as a defense mechanism against outside invaders. At roughly 1,312 by 328 feet, the structure could have housed a couple hundred people at any given time.

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