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Did a Cosmic Collision Dam the Grand Canyon? A 56,000-Year-Old Mystery

A remarkable coincidence occurred 56,000 years ago, when the impact that created Meteor Crater triggered both a landslide-dammed lake and a paleolake formation in the Grand Canyon. Earth’s ancient past often reads like a mystery novel, and a recent study published in Geology reveals one of its mo

Noncanonical and mortality-defining toxicities of CAR T cell therapy

This Review summarizes the current knowledge on mortality-defining toxicities of chimeric antigen receptor T cell therapies beyond cytokine-release syndrome and immune effector cell-associated neurotoxicity syndrome. The authors discuss underlying mechanisms and how these affect timing and management, and outline key unmet needs and future priorities.

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