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Studies of a “future-proof” vaccine candidate have shown that just one antigen can be modified to provide a broadly protective immune response in animals. The studies suggest that a single vaccine with combinations of these antigens—a substance that causes the immune system to produce antibodies against it—could protect against an even greater range of current and future coronaviruses.

The antigen technology, developed by the University of Cambridge and spin-out DIOSynVax in early 2020, provided protection against all known variants of SARS-CoV-2—the that causes COVID-19—as well as other major coronaviruses, including those that caused the first SARS epidemic in 2002.

The studies in mice, rabbits and guinea pigs—an important step before beginning , currently underway in Southampton and Cambridge—found that the provided a strong immune response against a range of coronaviruses by targeting the parts of the virus that are required for replication. The vaccine candidate is based on a single digitally designed and immune optimized antigen.

A single protein can self-assemble to build the scaffold for a biomolecular condensate that makes up a key nucleolar compartment.

Inside all living cells, loosely formed assemblies known as biomolecular condensates perform many critical functions. However, it is not well understood how proteins and other biomolecules come together to form these assemblies within cells.

MIT.

The boundaries of science are constantly being pushed and expanded as newer and more advanced technology is developed, and researchers are now promising a “new era” of discovery as the world’s most powerful X-ray laser comes online.

The laser in question is the Linac Coherent Light Source (LCLS) II, and it’s able to produce up to a million X-ray flashes every single second. That’s some 8,000 times more than the original LCLS laser, creating a virtually continuous beam of highly energetic light that is 10,000 times brighter than before.

That means it can capture processes in much more detail at the atomic scale, perhaps processes that have never been properly observed before – and from there, maybe opening up completely new fields of research.

As if being Earth’s largest sphere and having giant LED screens inside and out wasn’t enough, the MSG Sphere has announced its next plan to take Las Vegas to the future with robots.

Sphere Entertainment introduced the world to Aura, the world’s most advanced humanoid robot, that will permanently reside at the arena when it launches this month.

Five Aura robots are located at the venue’s grand atrium greeting guests as they enter and will be available to answer questions, according to MSG Ventures CEO David Dibble. The “spokesbots” will maintain life-like facial expressions and mobility on full display.

For centuries now science has unlocked ever more mysteries, but could we one day run out of discoveries or abandon further research?

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