Toggle light / dark theme

Longevity Investor Network member Sebastian Aguiar discusses the rejuvenation biotechnology industry and bridging the gap between research and development.


Sebastian Aguiar is a Venture Fellow at Apollo Ventures, an aging-focused venture capital fund and company builder that invests across Europe and the United States. He can be found at https://www.linkedin.com/in/sebastianaguiar/ and https://twitter.com/sebastian_gero.

What initially attracted you to aging as a general discipline?

Aging is already a solved problem… for cells. The germ line is immortal. Cancer cells are immortal as well. In fact, cellular immortality has been a solved problem for 3.5 billion years, since the dawn of life on Earth. It’s just that the soma – all the cells other than the reproductive cells – are disposable.

Read more

Saying farewell to coffee isn’t that easy. According to research about three-fifths of all our beloved coffee species are going to go extinct. This is a phenomenal amount of coffee that we risk losing.

Here’s something to think about as you sip that morning mochaccino:?Deforestation, climate change and the proliferation of pests and fungal pathogens are putting most of the world’s wild coffee species at risk of extinction.

At least 60 percent of wild coffee species are considered “threatened,” according to a study published this week in Science Advances. And fewer than half of all the wild species are safeguarded in so-called germplasm collections—banks for seed and living plants kept in protected areas as backups.

Read more

Innovation in fashion is sparking radical change. In the future clothes could be computers, made with materials designed and grown in a lab.

Click here to subscribe to The Economist on YouTube: https://econ.st/2xvTKdy

A new wave of innovation is fueling a radical change in fashion. Wearable technology, data, automation and lab-grown materials will have a major impact on what people will be wearing in the future.

Since the birth of sewing and weaving, technology has always led developments in fashion. The Industrial Revolution mechanized manufacturing enabling mass production. In the 1960s synthetic materials like polyester took off, creating new possibilities for fashion.

Now the convergence of new technologies is opening up previously unimaginable possibilities. Self-styled fashion scientist Dr Amanda Parkes is in the vanguard of the industry’s latest reinvention. She heads up innovation at FT labs, a venture capital firm that invests primarily in disruptive fashion tech startups. Among these startups the race is on to find the next generation of renewable materials that can be grown in a lab. Traditional silk is produced from insect larvae that form cocoons, most commonly silkworms. But rather than relying on these insects bolt threads is creating silk in test tubes. Bio fabricated materials remove the need for animals and insects and they are a more sustainable and efficient way of producing raw materials.

Other companies are creating leather alternatives. Rather than using animals scientists are creating bio fabricated materials from pineapple leaves and even mushrooms. The convergence of fashion and technology also provides opportunities to transform not just clothes but the people wearing them.

#MachineLearning and #ArtificialIntelligence are revolutionising the online world. They are capable of reducing costs, analysing data, recognising patterns and trends we can’t see with the human eye and making real- time decisions. Now, they are being used to help prevent financial fraud and they’re learning how to do it better every day.


Machine learning and artificial intelligence are revolutionising the online world. They are capable of reducing costs, analysing data, recognising patterns and trends we can’t see with the human eye and making real-time decisions. Now, they are being used to help prevent financial fraud and they’re learning how to do it better every day.

Currently it is estimated that cybercrime costs the global economy approximately $600 billion, with one of the most common forms being credit card fraud which has grown considerably with the increase in the online market. As more and more people chose to transact online it is becoming increasingly important for financial services to invest in better, faster and more accurate fraud detection and prevention techniques.

How our data helps protect us

Thanks to there being such a large amount of online transactions, this means that there is a huge amount of customer data available which can be studied and learnt by AI. They can learn how to identify valid credit card behavioural patterns and how to detect irregular behaviour which could be fraudulent.

Read more

As if battered post-Christmas finances, a looming disorderly Brexit and the prospect of a fresh nuclear arms race were not enough to dampen spirits, astronomers have declared that a nearby galaxy will slam into the Milky Way and could knock our solar system far into the cosmic void.

The unfortunate discovery was made after scientists ran computer simulations on the movement of the Large Magellanic Cloud (LMC), one of the many satellite galaxies that orbits the Milky Way. Rather than circling at a safe distance, or breaking free of the Milky Way’s gravitational pull, the researchers found the LMC is destined to clatter into the galaxy we call home.

At the moment, the LMC is estimated to be about 163,000 light years from the Milky Way and speeding away at 250 miles per second. But simulations by astrophysicists at Durham University show that the LMC will eventually slow down and turn back towards us, ultimately smashing into the Milky Way in about 2.5 billion years’ time.

Read more

The 3 key ingredients for attracting investors to your crowdfunding (ICO/STO) campaign

Below is a redacted and slightly edited and updated version of a memo provided to a client regarding how to attract investors to their business, in mid 2017. For background, they’re a 5 year old private investment firm, whose stock is traded OTC and who invest in startups focused on blockchain tech. To further this model they were exploring additional ways to raise capital, specifically to acquire more startups. Below is a high level framework of what investor “whales” are looking for. This is not investment advice. These are redacted insights into what you should be considering if you’re looking to also engage potential investors in your business enterprise.

If you don’t have time to read it all, I’ll summarize: It still takes money to make money.

Note — all crowdfunding campaigns (regardless of if you call them ICOs / STOs) require a legitimate business model, tangible solutions to real problems, market size worth investing in and the potential for 100x returns. Otherwise, whales aren’t interested in 10x returns.

I owe Jack Shaw a favor. It’s one of those, “This one time in Cambodia…” type of favors. We won’t speak of it beyond perhaps a nod and wink. It’s not written down anywhere; the details of such are so vague as to be almost non existent, while encompassing the known universe. It expires upon death, of the sun; and can be redeemed whenever and by another person who need only walk up to me and say, “Jack Shaw sent me. He says to tell you ________”. And tada, that favor has been redeemed for value.

Jack would call this favor a “marker.” It’s more valuable than your house, the Empire State Building & 100k Bitcoins combined. It can even be redeemed for something even more precious, my time or an opportunity or access to my network. You know, those things that money can’t buy. Well, you can lease my time from time to time.

Favors, markers and promises are humanities’ first virtual currencies.

They’ve gone digital recently, as Jack might redeem his marker via a WhatsApp or WeChat text message.

Favors and promises aren’t financial obligations per-say. They’re moral debts that can be redeemed for things of intrinsic, monetary, social and/or actual value. Now, here is where things get a little weird. The thing about “money” is that it doesn’t have any value. It’s actually a reflection of a moral debt. Hence why the US dollar is backed by the “Full Faith and Credit of the US Government” and not say, gold or wheat. You believe…that people will feel obligated to pay taxes and in turn the government will collect these social obligations (aka favors) for the good and benefit of The People. This moral obligation is part of that “Debt to Society” you’ve heard so much about, are obligated to pay, but don’t recall actually signing up for.

Long ago, these virtual currencies of favors, promises, social obligations and credits were turned into what we now regard as money. Not because paper money or coins had or have any intrinsic value, but because for trade beyond one’s family or clan, it’s easier to convey/store and document the value of Sam owing you two chickens, using cash as that documentation (or store of value). As you extended to him a two chicken line of credit.

“Credit” is just another favor or marker with terms.

Coins and “Banknotes” (because people wrote down how much credit they gave you) were just the earliest form of noting and coming to consensus on how to document these virtual currencies of favors, markers, promises and credit.

Overtime, what favor or credit money represents has been lost. We’ve been conditioned to simply believing (Full Faith and Credit) that paper money has intrinsic value, when it simply doesn’t.

Paper money isn’t backed backed by anything other than your faith.

Hence why inflation is such a troublesome concept for most. It challenges the fundamental principles of your faith — every time the government prints more paper money. It extends to itself (and then to you, via banks) made up and virtual favors by the billions. They are favors and markers with no value behind them; lines of credit with no chickens attached. So when these virtual chickens come home to roost, as actual value, guess what? There aren’t any chickens, just a whole lotta hungry believers.

Everybody believes in this system of virtual currencies of credit, favor and marker collection, except the banks and the corporations who effectively pay zero in taxes, while simultaneously collecting trillions in credits from people and then turning those virtual dollars into “real wealth.” Think real estate.

Fun fact/Tangent: Why is real estate called “real?” Hint: It has something to do with the fact that money has no value (isn’t real) but shelter/housing does. We’ll talk about how banks and corporations got out of their social contract at your expense later.

In 1961, Nancy Grace Roman was already the first Chief of Astronomy in NASA’s Office of Space Science. She developed that program in a time before the second wave of the Women’s Movement in the United States began, when banks often refused women credit in their own names and there was still an active medical debate about whether women could ever physically endure spaceflight someday. But Roman opened the skies to humanity in new ways without ever leaving the ground.

She earned her Ph.D. in astronomy at the University of Chicago in 1949 and worked at the Yerkes Observatory there for six years afterward. She joined the radio astronomy group at the Naval Research Laboratory, becoming the head of the microwave spectroscopy section. As she recalled in 1980 in an oral history interview with National Air and Space Museum curator David DeVorkin, when she heard that NASA might set up a space astronomy program, she wanted to lead it: “The idea of coming in with an absolutely clean slate to set up a program that I thought was likely to influence astronomy for 50 years was just a challenge that I couldn’t turn down. That’s all there is to it.” She joined NASA in 1959, just after the agency’s founding.

Roman opened the skies to humanity in new ways without ever leaving the ground.

Read more

It is an eye opening video. In the financial climate we are now I am not shocked that these Miners are losing based on costs.


I wrote an article on the Wave Chronicle regarding the Crypto-Currency Crash and some of the changes that could be made to make this particular market effective for those who actually want to use Crypto-Currency as a vehicle for purchasing.

http://wavechronicle.com/wave/?p=70621

I came across a video which.