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Team uses 3D tissue engineering to revolutionize dental disease

The discomfort and stigma of loose or missing teeth could be a thing of the past as Griffith University researchers pioneer the use of 3D bioprinting to replace missing teeth and bone.

The three-year study, which has been granted a National Health and Medical Research Council Grant of $650,000, is being undertaken by periodontist Professor Saso Ivanovski from Griffith’s Menzies Health Institute Queensland.

As part of an Australian first, Professor Ivanovski and his team are using the latest 3D bioprinting to produce new, totally ‘bespoke,’ tissue engineered and gum that can be implanted into a patient’s jawbone.

DARPA Project to Seek Lightyear-Like Leap in Design, Manufacturing

With 3D printers; many small mom-and-pop manufacturers are easy to set up anywhere. Which brings in some interesting challenges when thinking about regulatory compliance and safety. Imaging a neighbor who was laid off gets a 3D printer and begins building and shipping things from their home. Plus they’re stock piling chemicals and other things in their basement or garage as “bi-products” in the production of the goods that they are building with their $15K 3D printer. Question for many is — how safe is it? how can this be monitored and controlled?


Manufacturers haven’t been able to fully exploit advancements in new materials, because computer-aided design and engineering tools haven’t kept pace, says a program manager for the government agency.

Vandenbrande: Humans have reached limits of their imagination.

ORNL, UT Team Up on Breakthrough That Could Aid Quantum Computing

Another reason for being in east TN this month.


Genevieve Martin/ORNL This rendering illustrates the excitation of a spin liquid on a honeycomb lattice using neutrons. As with many other liquids, it is difficult to see a spin liquid unless it is “splashed,” in this case by neutrons depicted as moving balls. The misaligned and vibrating spin pair in the middle signifies the ephemeral Majorana fermion constantly in motion. The ripples formed when the neutrons hit the spin liquid represent the excitations that are a signature of the Majorana fermions. The atomic structure on the left signifies the honeycomb alpha-ruthenium trichloride, in which each ruthenium atom has a spin and is surrounded by a cage of chlorine atoms.

Researchers from the U.S. Department of Energy’s Oak Ridge National Laboratory and UT’s Department of Materials Science and Engineering and Department of Physics and Astronomy used neutrons to uncover novel behavior in materials that holds promise for quantum computing.

The findings, published in Nature Materials, provide evidence for long-sought phenomena in a two-dimensional magnet.

Dressed to kill: Tailoring a suit for tumor-penetrating cancer meds

Very cool.


For more than a decade, biomedical researchers have been looking for better ways to deliver cancer-killing medication directly to tumors in the body. Tiny capsules, called nanoparticles, are now being used to transport chemotherapy medicine through the bloodstream, to the doorstep of cancerous tumors. But figuring out the best way for the particles to get past the tumor’s “velvet rope” and enter the tumor is a challenge scientists are still working out. Drexel University researchers believe that the trick to gaining access to the pernicious cellular masses is to give the nanoparticles a new look—and that dressing to impress will be able to get them past the tumor’s biological bouncers.

Targeted cancer therapy is most effective when the medication is released as close as possible to the interior of a , to increase its odds of penetrating and killing off cancerous cells. The challenge that has faced cancer researchers for years is making a delivery vehicle that is sturdy enough to safely get the medication through the bloodstream to tumors—which is no smooth ride—but is also lithe enough to squeeze through the tumor’s dense extra cellular space—a matrix stuffed with sugars called hyaluronic acid.

In research recently published in the journal Nano Letters, lead author Hao Cheng, PhD, an assistant professor with an appointment in Drexel’s College of Engineering, and affiliation with School of Biomedical Engineering, Science and Health Systems; reports that the way to get past the tumor’s front door has everything to do with how the tiny particle is suited up for the journey.

Crumpling approach enhances photodetectors’ light responsivity

HUGE deal for wearables and biomed technologies.


Researchers from the University of Illinois at Urbana-Champaign have demonstrated a new approach to modifying the light absorption and stretchability of atomically thin two-dimensional (2D) materials by surface topographic engineering using only mechanical strain. The highly flexible system has future potential for wearable technology and integrated biomedical optical sensing technology when combined with flexible light-emitting diodes.

“Increasing graphene’s low light absorption in visible range is an important prerequisite for its broad potential applications in photonics and sensing,” explained SungWoo Nam, an assistant professor of mechanical science and engineering at Illinois. “This is the very first stretchable photodetector based exclusively on graphene with strain-tunable photoresponsivity and wavelength selectivity.”

Graphene—an atomically thin layer of hexagonally bonded carbon atoms—has been extensively investigated in advanced photodetectors for its broadband absorption, high carrier mobility, and mechanical flexibility. Due to graphene’s low optical absorptivity, graphene photodetector research so far has focused on hybrid systems to increase photoabsorption. However, such hybrid systems require a complicated integration process, and lead to reduced carrier mobility due to the heterogeneous interfaces.

Advance may make quantum computing more practical

Very nice; we’re getting closer.


But superposition is fragile, and finding ways to preserve it is one of the chief obstacles to developing large, general-purpose quantum computers. In today’s Nature, MIT researchers describe a new approach to preserving superposition in a class of quantum devices built from synthetic diamonds. The work could ultimately prove an important step toward reliable quantum computers.

In most engineering fields, the best way to maintain the stability of a physical system is feedback control. You make a measurement — the current trajectory of an airplane, or the temperature of an engine — and on that basis produce a control signal that nudges the system back toward its desired state.

The problem with using this technique to stabilize a quantum system is that measurement destroys superposition. So quantum-computing researchers have traditionally had to do without feedback.

International Petition against Autonomous Weapons

Stuart Russell received his B.A. with first-class honours in physics from Oxford University in 1982 and his Ph.D. in computer science from Stanford in 1986. He then joined the faculty of the University of California at Berkeley, where he is Professor (and formerly Chair) of Electrical Engineering and Computer Sciences and holder of the Smith-Zadeh Chair in Engineering. He is also an Adjunct Professor of Neurological Surgery at UC San Francisco and Vice-Chair of the World Economic Forum’s Council on AI and Robotics. He has published over 150 papers on a wide range of topics in artificial intelligence including machine learning, probabilistic reasoning, knowledge representation, planning, real-time decision making, multitarget tracking, computer vision, computational physiology, and global seismic monitoring. His books include “The Use of Knowledge in Analogy and Induction”, “Do the Right Thing: Studies in Limited Rationality” (with Eric Wefald), and “Artificial Intelligence: A Modern Approach” (with Peter Norvig).

Abstract:

Autonomous weapons systems select and engage targets without human intervention; they become lethal when those targets include humans. LAWS might include, for example, armed quadcopters that can search for and eliminate enemy combatants in a city, but do not include cruise missiles or remotely piloted drones for which humans make all targeting decisions. The artificial intelligence (AI) and robotics communities face an important ethical decision: whether to support or oppose the development of lethal autonomous weapons systems (LAWS).

ORNL 20kW wireless charging system hits 90% efficiency

Oak Ridge National Laboratory (ORNL) has been working on a wireless charging system for EVs and plug-in hybrids for years. The goal is to create a system that makes charging EVs and hybrids easier for drivers and to make EVs and other plug-in vehicles as cheap and easy to own as a gasoline vehicle. ORNL has announced that it has demonstrated a 20-kilowatt wireless charging system that has achieved 90% efficiency at three times the rate of the plug-in systems commonly used in electric cars today.

ORNL has multiple industry partners that are participating in this program including Toyota, Cisco Systems, Evatran, and Clemson University International Center for Automotive Research. “We have made tremendous progress from the lab proof-of-concept experiments a few years ago,” said Madhu Chinthavali, ORNL Power Electronics Team lead. “We have set a path forward that started with solid engineering, design, scale-up and integration into several Toyota vehicles. We now have a technology that is moving closer to being ready for the market.”

The wireless charging system includes ORNL-built inverter, isolation transformer, vehicle-side electronics and coupling technologies, and it was built in under three years. The demonstrator system is integrated into a Toyota RAV4 with a 10kW battery. The next goal for the researchers is to create a 50kW wireless charging system that can match the power of commercially available quick plug-in chargers. These higher power-charging systems are essential for charging larger electrified vehicles like buses and trucks.

Researchers have worked out how to mind control cockroaches

In a video presented at IEEE Robotics and Automation Society’s annual conference, Chinese engineering students guide a living cockroach along S-shaped and Z-shaped paths using brain-to-brain interface: a bluetooth electroencephalogram (EEG) headset, translated and wirelessly sent to an electronic backpack receiver attached to the cockroach. The electrical impulses then stimulated the antennae nerves of the cockroach through a microelectrode implanted into its head. Watch the video released:

(Announced 16 June 2015 but only just came to our attention. And no, this is not April Fools post.)