Lifeboat Foundation: Safeguarding Humanity
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Category: engineering – Page 146

There’s quite a bit of buzz these days about how humanity could become a “multiplanetary” species. This is understandable, considering that space agencies and aerospace companies from around the world are planning on conducting missions to low earth orbit (LEO), the moon, and Mars in the coming years, not to mention establishing a permanent human presence there and beyond.

To do this, humanity needs to develop the necessary strategies for sustainable living in hostile environments and enclosed spaces. To prepare humans for this kind of experience, groups like Habitat Marte (Mars Habitat) and others are dedicated to conducting simulated missions in analog environments. The lessons learned will not only prepare people to live and work in space but foster ideas for sustainable living here on Earth.

Habitat Marte was founded in 2017 by Julio Francisco Dantas de Rezende, the professor of sustainability in the Department of Product Engineering at the Federal University of Rio Grande do Norte (UFRN) and the director of innovation with the Research Support Foundation (FAPERN). He is also the coordinator of Habitat Marte and Mars Society Brazil.

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Tweaking an immune protein called interleukin-18 can overcome tumors that lure it into binding with a decoy receptor protein and render it harmless to cancer cells, new research in mice shows. In conjunction with the paper, published Wednesday in Nature, a company founded by senior author Aaron Ring announced $25 million in initial financing to create and commercialize a drug based on the discovery.

The approach adds another weapon to an immunotherapy arsenal that activates immune responses hijacked by cancer. Checkpoint inhibitors, for example, take the brakes off immune cells that should battle invaders. IL-18 is a cytokine that normally activates T cells and natural killer cells, two immune forces that fight infection, but it’s disarmed by the decoy wielded by tumors.

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Aliens & Black Holes

Penrose predicted that the object would acquire a negative energy in this unusual area of space. By dropping the object and splitting it in two so that one half falls into the black hole while the other is recovered, the recoil action would measure a loss of negative energy—effectively, the recovered half would gain energy extracted from the black hole’s rotation. The scale of the engineering challenge the process would require is so great, however, that Penrose suggested only a very advanced, perhaps alien, civilisation would be equal to the task.

A 50-year-old theory that began as speculation about how an alien civilization could use a black hole to generate energy has been experimentally verified for the first time in a Glasgow research lab.

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Automated tabletop machine could accelerate the development of novel drugs to treat cancer and other diseases.

Many proteins are useful as drugs for disorders such as diabetes, cancer, and arthritis. Synthesizing artificial versions of these proteins is a time-consuming process that requires genetically engineering microbes or other cells to produce the desired protein.

MIT chemists have devised a protocol to dramatically reduce the amount of time required to generate synthetic proteins. Their tabletop automated flow synthesis machine can string together hundreds of amino acids, the building blocks of proteins, within hours. The researchers believe their new technology could speed up the manufacturing of on-demand therapies and the development of new drugs, and allow scientists to design artificial proteins by incorporating amino acids that don’t exist in cells.

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With a new nanoparticle that converts light to heat, a team of researchers has found a promising technology for clearing water of pollutants.

Trace amounts of contaminants such as pesticides, pharmaceuticals and perfluorooctanoic acid in drinking water sources have posed significant health risks to humans in recent years. These micropollutants have eluded conventional treatment processes, but certain chemical processes that typically involve ozone, hydrogen peroxide or UV light have proven effective. These processes, however, can be expensive and energy-intensive.

A new nanoparticle created by Yale University engineers as part of an effort for the Rice-based Nanosystems Engineering Research Center for Nanotechnology-Enabled Water Treatment (NEWT) could lead to technologies that get around those limitations. The particle is described in a study published this week in the Proceedings of the National Academy of Sciences.

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Circa 2016

Biomedical research is contributing significant role in the field of biomedical engineering and applied science. It brings research and innovations to a different level. This study investigated artificial human blood –synthetic plasma liquid as conductive medium. Keeping in mind the conductivity of synthetic plasma, astable multivibrator as well as differential amplifier circuit were demonstrated. The circuits were given normal input voltages at regular temperature and ideal conditions. The result shows desired response which supports the novel concept. For both the circuits, phase shift of 180° achieved by analysing biological electronic circuits.

Keywords: Synthetic plasma, biomedical science, human body.

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A Tesla Model 3 has been modified with a solar roof as part of Lightyear’s solar car development program.

We have been reporting on Lightyear for a few years now.

The startup first caught our attention because it spun out of Solar Team Eindhoven, a group of engineering students from the Technical University of Eindhoven (Netherlands) who have been competing in the World Solar Challenge with their Stella and Stella Lux, energy positive solar cars — meaning that they can produce more energy than they consume.

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Accelerating progress in neuroscience is helping us understand the big picture—how animals behave and which brain areas are involved in bringing about these behaviors—and also the small picture—how molecules, neurons, and synapses interact. But there is a huge gap of knowledge between these two scales, from the whole brain down to the neuron.

A team led by Christos Papadimitriou, the Donovan Family Professor of Computer Science at Columbia Engineering, proposes a new computational system to expand the understanding of the brain at an intermediate level, between and cognitive phenomena such as language. The group, which includes computer scientists from Georgia Institute of Technology and a neuroscientist from the Graz University of Technology, has developed a brain architecture that is based on neuronal assemblies, and they demonstrate its use in the syntactic processing in the production of language; their model, published online June 9 in PNAS, is consistent with recent experimental results.

“For me, understanding the brain has always been a computational problem,” says Papadimitriou, who became fascinated by the brain five years ago. “Because if it isn’t, I don’t know where to start.”

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Engineers at Duke University have demonstrated a versatile microfluidic lab-on-a-chip that uses sound waves to create tunnels in oil to touchlessly manipulate and transport droplets. The technology could form the basis of a small-scale, programmable, rewritable biomedical chip that is completely reusable to enable on-site diagnostics or laboratory research.

The results appear online on June 10 in the journal Science Advances.

“Our new system achieves rewritable routing, sorting and gating of droplets with minimal external control, which are essential functions for the digital logic control of droplets,” said Tony Jun Huang, the William Bevan Distinguished Professor of Mechanical Engineering and Materials Science at Duke. “And we achieve it with less energy and a simpler setup that can control more droplets simultaneously than previous systems.”

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