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Category: business – Page 25

How far till Longevity Escape Velocity?

They say aging is just a part of life, but have you ever wondered if it really has to be? What if getting older isn’t just something we accept but something we could actually treat?

In this riveting episode of Peak Human Labs Podcast, Dr. Sanjeev Goel, sits down with Dr. Aubrey de Grey, a trailblazing biomedical gerontologist and Chief Science Officer of the SENS Research Foundation. They dive deep into the revolutionary idea of treating aging as a medical condition. They explore how damage accumulates in our bodies over time and discuss the groundbreaking medical advancements that could extend our healthy lifespans. Dr. de Grey sheds light on the crucial need for investing in underfunded research and shares insights into the future of longevity science. Tune in and envision a future where health and longevity are not just aspirations but achievable realities!

Click https://dublinlongevitydeclaration.or… to sign in for Dublin Longevity Declaration.

In This Episode:

[00:00:00] Introduction to longevity research.
[00:00:51] Guest introduction.
[00:01:17] Personal connection.
[00:02:04] Dr. de Grey’s background.
[00:03:14] Early research stages.
[00:04:05] Understanding aging as a machine.
[00:05:22] Accumulated damage mechanism.
[00:06:15] Comprehensive medical control.
[00:07:13] Categories of damage.
[00:07:55] Wear and tear concept.
[00:09:20] Epigenetic changes discussion.
[00:11:31] Partial reprogramming concept.
[00:13:30] Addressing multiple mechanisms.
[00:14:31] Longevity escape velocity.
[00:15:43] Initial pushback on longevity ideas.
[00:17:51] Positive outlook on aging research.
[00:19:51] The future of longevity research.
[00:20:54] Funding disparities in research.
[00:21:10] Business models in longevity research.
[00:21:58] Combining existing therapies.
[00:23:47] Current longevity therapies.
[00:24:56] Caloric restriction vs. drugs.
[00:25:36] Dublin Longevity Declaration.
[00:26:39] Community building through conferences.
[00:28:09] Anticipating longevity breakthroughs.
[00:29:12] Access to longevity therapies.
[00:30:58] Epigenetic clocks and age reversal.
[00:32:24] Retroviruses and aging.
[00:34:56] Persistent viral infections.
[00:37:24] Hyperbaric oxygen therapy.
[00:37:49] Therapeutic blood exchange.
[00:39:37] Discussion on active ingredients.
[00:40:41] Bone marrow transplant experimentation.
[00:42:09] Health benefits of bone marrow transplants.
[00:43:05] Personal health practices.
[00:43:55] Advice for maximizing healthy lifespan.
[00:45:01] Microbiome and longevity.

Breakthrough from REMspace: First Ever Communication Between People in Dreams

REDWOOD CITY, Calif.—()—Researchers at REMspace, a California-based startup, have achieved a historic milestone, demonstrating that lucid dreams could unlock new dimensions of communication and humanity’s potential. Using specially designed equipment, two individuals successfully induced lucid dreams and exchanged a simple message.

Watch the experiment here.

Lucid dreams occur when a person is aware they are dreaming while still in the dream state. This phenomenon happens during REM sleep and has numerous potential applications, from solving physiological problems to learning new skills. In earlier research, REMspace demonstrated that facial electromyography sensors could decode specific sounds made in dreams. This led to the development of Remmyo, a dream language detectable through sensitive sensors.

AI Researcher Slams OpenAI, Warns It Will Become the “Most Orwellian Company of All Time”

In the last few months, the mask has really come off.

OpenAI is far from its days of being an altruistic, non-profit company.

It is now the face of a booming AI industry and is effectively for-profit in all but name, steaming ahead with little regard for its technology’s environmental toll, or for the potentially existential risks it poses to society.

But according to Gary Marcus, a cognitive scientist and prominent AI researcher, the worst is yet to come. In his assessment, OpenAI could soon take an even more dystopian pivot, à la George Orwell’s novel “1984,” by getting into the business of spying on you.

Breaking up big tech: US wants to separate Android, Play, and Chrome from Google

The US Department of Justice (DoJ) has submitted a new “Proposed Remedy Framework” to correct Google’s violation of antitrust antitrust laws in the country (h/t Mishaal Rahman). This framework seeks to remedy the harm caused by Google’s search distribution and revenue sharing, generation and display for search results, advertising scale and monetization, and accumulation and use of data.

The most drastic of the proposed solutions includes preventing Google from using its products, such as Chrome, Play, and Android, to advantage Google Search and related products. Other solutions include allowing websites to opt-out of training or appearing in Google-owned AI products, such as in AI Overviews in Google Search.

Google responded to this by asserting that “DOJ’s radical and sweeping proposals risk hurting consumers, businesses, and developers.” While the company intends to respond in detail to DoJ’s final proposals, it says that the DoJ is “already signaling requests that go far beyond the specific legal issues in this case.”

Scientists Are Closer Than Ever To Reverse Aging. How Does It Work? | Life Extended

Billionaires are backing top scientists racing to develop tech that could reverse aging. Cellular reprogramming promises to rejuvenate the body… but how does it work, and is it safe?

00:00 – Introduction.
00:55 – The Role Of Stem Cells.
02:33 – What Is Aging?
03:24 – What Is Cellular Reprogramming?
03:56 – How The Yamanaka Factors Can Rejuvenate Cells.
05:35 – Why Scientists Want To Partially Reprogram Cells.
06:28 – How Humans Could Become More Resilient To Age-Related Diseases.
07:00 – How Johnny Huard Uses Cellular Reprogramming.
08:10 – How Cellular Reprogramming Could Shape The Future.
08:38 – Amazon’s Jeff Bezos Is Investing Billions With Altos Labs.
09:02 – How Harvard Professor David Sinclair Used Cellular Reprogramming on Mice.
10:07 – ChatGPT’s Sam Altman Launched Retro. Biosciences.
10:57 – The Risks of Cellular Reprogramming, Including Cancer.
12:56 – How the Tech World Is Investing In Biotech.
13:50 – Credits.

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Vulnerable APIs and Bot Attacks Costing Businesses Up to $186 Billion Annually

Organizations are losing between $94 — $186 billion annually to vulnerable or insecure APIs (Application Programming Interfaces) and automated abuse by bots. That’s according to The Economic Impact of API and Bot Attacks report from Imperva, a Thales company. The report highlights that these security threats account for up to 11.8% of global cyber events and losses, emphasizing the escalating risks they pose to businesses worldwide.

Drawing on a comprehensive study conducted by the Marsh McLennan Cyber Risk Intelligence Center, the report analyzes over 161,000 unique cybersecurity incidents. The findings demonstrate a concerning trend: the threats posed by vulnerable or insecure APIs and automated abuse by bots are increasingly interconnected and prevalent. Imperva warns that failing to address security risks associated with these threats could lead to substantial financial and reputational damage.

OpenAI Announces $6.6 Billion in Funding, Nearly Doubling Valuation to $157 Billion

Artificial-intelligence tech company OpenAI said it has raised $6.6 billion in new funding, giving it a massive post-money valuation of $157 billion, almost double its previous reported valuation of $80 billion earlier this year.

The new round of funding was led by venture-capital firm Thrive Capital, with additional investors including Microsoft, Nvidia, SoftBank, Fidelity, Khosla Ventures, Altimeter Capital, United Arab Emirates-based MGX and Tiger Global. In 2024, OpenAI is projecting a $5 billion net loss on $3.7 billion in revenue, CNBC reported. Next year, the company is targeting $11.6 billion in revenue, per the report.

“We are making progress on our mission to ensure that artificial general intelligence benefits all of humanity,” OpenAI said in a statement announcing the funding. “Every week, over 250 million people around the world use ChatGPT to enhance their work, creativity and learning. Across industries, businesses are improving productivity and operations, and developers are leveraging our platform to create a new generation of applications. And we’re only getting started.”

Stanford Medicine study hints at ways to generate new neurons in old brains

The same technique could also be applied to studies of brain damage, Ruetz said. “Neural stem cells in the subventricular zone are also in the business of repairing brain tissue damage from stroke or traumatic brain injury.”

The glucose transporter connection “is a hopeful finding,” Brunet said. For one, it suggests not only the possibility of designing pharmaceutical or genetic therapies to turn on new neuron growth in old or injured brains, but also the possibility of developing simpler behavioral interventions, such as a low carbohydrate diet that might adjust the amount of glucose taken up by old neural stem cells.

The researchers found other provocative pathways worthy of follow-up studies. Genes relating to primary cilia, parts of some brain cells that play a critical role in sensing and processing signals such as growth factors and neurotransmitters, also are associated with neural stem cell activation. This finding reassured the team that their methodology was effective, partly because unrelated previous work had already discovered associations between cilia organization and neural stem cell function. It is also exciting because the association with the new leads about glucose transmission could point toward alternative avenues of treatment that might engage both pathways, Brunet said.