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Jun 12, 2024

Dementia Breakthrough: Brain Scans Predict Disease Up to 9 Years Early

Posted by in categories: biotech/medical, neuroscience

Diagnosing dementia early gives us more time to put precautions in place and to study exactly how the condition progresses – and a new method for predicting conditions such as Alzheimer’s disease is promising up to nine years of advance warning.

The method, developed by a team from the Queen Mary University of London in the UK and Monash University in Australia, involves a neurobiological model that analyzes brain scans captured by functional magnetic resonance imaging, or fMRI.

In tests, the model was more than 80 percent accurate at predicting the development of dementia. That has huge potential in terms of early diagnosis, and it also addresses another challenge: the large number of people with dementia who don’t get diagnosed at all.

Jun 12, 2024

A jet missing since 1971 has been found at the bottom of Vermont’s Lake Champlain

Posted by in category: transportation

Fifty-three years after a private plane carrying five men disappeared on a snowy Vermont night, experts believe they have found the wreckage of the long lost jet in Lake Champlain.

The corporate jet disappeared shortly after departing the Burlington airport for Providence, Rhode Island, on Jan. 27, 1971. Those aboard included two crew members and three employees of a Georgia development company Cousins Properties, who were working on a development project in Burlington.

Initial searches for the 10-seat Jet Commander turned up no wreckage and the lake froze over four days after the plane was lost. At least 17 other searches happened, until underwater searcher Garry Kozak and a team using a remotely operated vehicle last month found wreckage of a jet with the same custom paint scheme in the lake close to where the radio control tower had last tracked the plane before it disappeared. Sonar images were taken of the wreck found in 200 feet of water near Juniper Island.

Jun 12, 2024

Astrophotographer gets close-up look at monster sunspot that led to May’s global auroras

Posted by in category: cosmology

Follow along step by step with astrophotographer Miguel Claro in this behind-the-scenes look at how such a mesmerizing solar photograph was made.

Jun 12, 2024

Have you seen Steve? Look up and you might spot the sky phenomenon

Posted by in category: futurism

The vibrant and elusive light stripe is not an aurora.

Jun 12, 2024

First Promethium ‘Complex’ Created, Revealing Mysterious Element’s Secrets

Posted by in categories: chemistry, nuclear energy, particle physics

Promethium, one of the rarest and most mysterious elements in the periodic table, has finally given up some crucial chemical secrets.

By Mark Peplow & Nature magazine

One of the rarest and most mysterious elements in the periodic table has finally given up some crucial chemical secrets, eight decades after its discovery. Researchers at Oak Ridge National Laboratory in Tennessee have become the first to use radioactive promethium to make a chemical ‘complex’ — a compound in which it is bound to a few surrounding molecules. This feat of synthesis enabled the team to study how the element bonds with other atoms in a solution with water. Published May 22 in Nature the findings fill a long-standing gap in chemistry textbooks, and could eventually lead to better methods for separating promethium from similar elements in nuclear waste, for example.

Jun 12, 2024

Dr. Susan Domchek, MD — Executive Director, Basser Center for BRCA, Abramson Cancer Center, Penn

Posted by in category: biotech/medical

Jun 12, 2024

Tesla claims it has 2 Optimus humanoid robots working autonomously in factory

Posted by in categories: Elon Musk, robotics/AI

Tesla claims that it currently has two Optimus humanoid robots working autonomously in a factory, which would be a first.

If there’s one good thing about this compensation package mess going on right now is that it almost looks like Tesla has a PR department again.

Sure, its raison d’etre is almost entirely about trying to get Elon Musk his $55 billion pay package back, but at least, they are putting some more information about Tesla out there in the process.

Jun 12, 2024

Development and Evolution of the Human Neocortex

Posted by in categories: evolution, neuroscience

The size and surface area of the mammalian brain are thought to be critical determinants of intellectual ability. Recent studies show that development of the gyrated human neocortex involves a lineage of neural stem and transit-amplifying cells that forms the outer subventricular zone (OSVZ), a proliferative region outside the ventricular epithelium. We discuss how proliferation of cells within the OSVZ expands the neocortex by increasing neuron number and modifying the trajectory of migrating neurons.

Jun 12, 2024

Scientists Reveal the Absolutely Metal Physics of Wormholes

Posted by in categories: climatology, cosmology, physics

Accreting wormholes likely form “plasma tornadoes” in its throat while firing matter at one-fifth the speed of light.

Jun 12, 2024

Some Breast Cancer Treatments Linked to Long-term Cardiovascular Disease Risk

Posted by in category: biotech/medical

Some breast cancer survivors are at higher risk for cardiovascular disease following certain treatments. A new study is one of the first to provide evidence that may inform long-term and age-specific monitoring for these adverse outcomes. Researchers observed that breast cancer survivors treated with anthracyclines, a type of chemotherapy, and/or trastuzumab, a targeted cancer therapy, had an increased long-term risk of cardiovascular disease, specifically cardiomyopathy/heart failure, compared to women who did not receive chemotherapy. This study was published in the Journal of the National Cancer Institute on May 8, 2024, and was selected for the journal’s Early Career Investigator Research Section.

It is well established that certain breast cancer treatments, such as anthracycline and trastuzumab, can lead to heart damage, which contributes to a higher risk of cardiovascular disease later in life. However, current guidelines only recommend short-term cardiovascular surveillance up to two years after anthracycline and trastuzumab treatment because of a lack of evidence regarding long-term risks. Jacqueline B. Vo, Ph.D., R.N., M.P.H., assistant clinical investigator in the Radiation Epidemiology Branch (REB), led a team of researchers from REB, the Integrative Tumor Epidemiology Branch, the National Heart, Lung, and Blood Institute, and Kaiser Permanente, to explore whether patients could benefit from long-term surveillance. Their analysis included over 10,000 breast cancer survivors in the NCI-Kaiser Permanente Breast Cancer Survivors Cohort with up to 24 years of follow up.

They found that breast cancer survivors, especially those diagnosed at younger ages, had higher risks of cardiovascular disease and could benefit from long-term cardiovascular follow-up. Specifically, risk of cardiomyopathy/heart failure were highest 10+ years after breast cancer diagnosis. Women who were diagnosed prior to age 55 had the highest risks for cardiomyopathy/heart failure, which was nearly three times higher compared to women the same age who did not receive chemotherapy. One reason for the higher risk of cardiomyopathy/heart failure among women diagnosed with breast cancer at younger ages is that this group is more likely to be diagnosed with more aggressive and/or advanced tumors, which are more likely to be treated with anthracyclines and at higher doses. These results highlight the importance of extending current treatment-specific clinical guidelines for cardiovascular surveillance to include longer follow-up and focus on high-risk patients such as younger women.

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