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Apr 22, 2024

Liver-Based Signaling Protects Tumors by Restraining Anticancer Immune Cells

Posted by in category: biotech/medical

“We want to better understand what causes cancer to resist or respond to immunotherapy to help design more effective strategies for patients,” said senior author Gregory Beatty, MD, PhD, an associate professor of hematology-oncology and the director of clinical and translational research for the Penn Pancreatic Cancer Research Center. “Our findings show that liver cells—with their release of SAA proteins—effectively serve as an immune checkpoint regulating anticancer immunity, making them a promising therapeutic target.”

The study builds on previous research from the team, including co-lead authors Meredith Stone, PhD, a research associate, and Jesse Lee, a graduate student, into liver inflammation in cancer: In a 2019 study, they showed how it promotes pancreatic tumor metastasis to that organ. In 2021, researchers from the Beatty Lab observed that systemic inflammation, involving many of the same molecules implicated in liver metastasis, is associated with worse responses to immunotherapies in pancreatic cancer patients.

The latest study was designed to investigate in more detail how liver inflammation may block the effects of these immune-boosting therapies.

Apr 22, 2024

After AI beat them, professional go players got better and more creative

Posted by in category: robotics/AI

From the article:

Were the moves getting better because some players cheated by using the AI?


For many decades, it seemed professional Go players had reached a hard limit on how well it is possible to play. Then AI beat them.

Apr 22, 2024

Scientists Say Something Seems to Have Broken Off the Moon at This Crater

Posted by in category: space

A team of astronomers believes the near-Earth asteroid Kamo’oalewa, a space rock between 130 and 328 feet in diameter, was once part of the Moon.

More specifically, a research team led by Tsinghua University astronomer Yifei Jiao suggests the rock was gouged from a geological feature on the far side of the Moon called the Giordano Bruno crater, named after a 16th-century Italian cosmological theorist.

“We have explored the processes for impact-induced lunar fragments migrating into Earth co-orbital space and presented support for Kamo’oalewa’s possible origin from the formation of the Giordano Bruno crater a few million years ago,” the researchers write in their paper published in the journal Nature Astronomy last week.

Apr 22, 2024

Meta rolls out new Meta AI website, and it might just bury Microsoft and Google’s AI dreams

Posted by in category: robotics/AI

Meta AI has gotten an upgrade and a new web interface, and it just might be the true ChatGPT killer.

Apr 22, 2024

Saudi Arabia is desperately trying to woo bankers to pay for its futuristic desert city

Posted by in category: futurism

Saudi Arabia hopes that bankers will shell out cash once they see the progress on its futuristic desert city, Neom, in person.

Apr 22, 2024

Generative AI In The Classroom: Next Edtech Evolution

Posted by in categories: education, robotics/AI

Revision bots, design-your-own-course companions, even mock interview coaches: Experts say that edtech is facing disproportionate disruption from generative AI, and interestingly, from older, non-tech learners in India.

Apr 22, 2024

International Space Station crew find ‘drug-resistant bacteria’ and have no idea how it got there

Posted by in categories: biotech/medical, evolution

I found this on NewsBreak:


The crew of the International Space Station has stumbled upon a drug-resistant bacteria on board, leaving them baffled as to how it arrived.

Scientists working in the low orbit lab have confirmed the discovery, which raises concerns about the potential evolution of more robust bacteria that could defy current treatments. The unique microgravity environment of the ISS is suspected to be a factor in the bacteria’s persistence.

Continue reading “International Space Station crew find ‘drug-resistant bacteria’ and have no idea how it got there” »

Apr 22, 2024

Experiment Prepares to Test a Possible Second Purpose For Stonehenge

Posted by in category: futurism

I found this on NewsBreak: Experiment Prepares to Test a Possible Second Purpose For Stonehenge.

Apr 22, 2024

Physicist Claudia de Rham: ‘Gravity connects everything, from a person to a planet’

Posted by in category: cosmology

I found this on NewsBreak: Physicist Claudia de Rham: ‘Gravity connects everything, from a person to a planet’


The scientist on training as a diver, pilot and astronaut in order to understand the true nature of gravity, and why being able to describe what happens at the centre of a black hole is so important.

Apr 22, 2024

Mitochondrial Meltdown: The Energy Failure Behind Neurodegenerative Diseases

Posted by in categories: biotech/medical, neuroscience

I found this on NewsBreak: Mitochondrial Meltdown: The Energy Failure Behind Neurodegenerative Diseases.

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