A research team from HKU Engineering has pioneered a fundamentally new imaging strategy known as AIMED (Arbitrary illumination microscopy with encoded depth), which utilizes a sub-sampling approach. By integrating innovations in axial optical encoding with advanced computational image reconstruction, the AIMED technology enables a substantial increase in 3D imaging speed while enhancing photon safety, all with minimal additional system complexity. This breakthrough demonstrates significant advantages across efficiency, image quality, and system compatibility.

This work was conducted by the OMEGA laboratory under the leadership of Professor Kenneth K. Y. Wong of the Department of Electrical and Computer Engineering at the University of Hong Kong (HKU). The study is published in the journal Advanced Photonics.