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Coral study could help explain infertility and ovarian cancer by decoding cilia-driven fluid flows

A study by researchers at The University of Manchester, carried out alongside the Universities of Melbourne and Copenhagen, could hold the key to understanding the causes of long-term health problems, such as infertility and ovarian cancer.

The study, published in PRX Life, used a combination of high-resolution imaging, flow measurements, and mathematical modeling to examine fluid flows around corals that are driven by cilia—densely packed tiny hairs on the coral’s surface. The collective beating of the cilia contributes to the movement of fluid around the surface of the coral, regulating the animal’s immediate environment through the transport of particles such as oxygen.

The researchers found that heterogeneity in ciliary orientation —small variations in the direction individual cilia beat—can significantly boost transport efficiency. For substances that diffuse slowly through the fluid, this natural variability increased particle transport by more than 50% compared to perfectly aligned cilia. This contrasts with other biological systems, highlighting how coral cilia are uniquely adapted to their environment.

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