New multiplexed imaging technology using standard clinical MRI systems can simultaneously map more than 20 biomarkers in high resolution, providing a comprehensive view of the brain with a single scan.

Researchers at the University of Illinois Urbana-Champaign demonstrated the multiplexed MRI technology (MRx) by characterizing brain tumors and multiple sclerosis lesions—revealing different structural, physiological and molecular changes within the diseases. Led by Zhi-Pei Liang, a professor of electrical and computer engineering and a member of the Beckman Institute for Advanced Science and Technology at the U. of I., the team has reported its findings in the journal Nature.

“MRx can be a powerful tool for noninvasive tissue characterization, helping to advance personalized, precision and predictive medicine,” Liang said. “By providing rich, multidimensional biomarkers to capture disease progression and treatment response, this capability could open new opportunities for more precise diagnosis, individualized treatment planning and improved patient outcomes.”