This study reveals an atherosclerosis-associated signature in platelet-monocyte complexes from people living with HIV. @RuoqiaoW @ThakarLab @URochester_SMD

BackgroundMonocytes contribute to atherosclerosis by migrating into inflamed endothelium and differentiating into lipid‐laden macrophages. In people living with HIV, chronic inflammation increases atherosclerosis risk, yet the role of specific monocyte subsets remains unclear. We investigated how distinct monocyte populations contribute to vascular pathology in early HIV‐associated atherosclerosis.