A new model for alveolar macrophage–Mycobacterium tuberculosis (TB) interactions!
https://doi.org/10.1172/jci.insight.
Michael S. Glickman & team establish a stem cell–derived lung alveolar macrophage model to reveal itaconate functions differently between human macrophage types in the host defense against Mtb:
The figure: Brightfield and stained images of two macrophage populations.
1Immunology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
2Immunology and Microbial Pathogenesis Program, Weill Cornell Medicine, New York, New York, USA.
3Department of Medicine, University of Washington, Seattle, Washington, USA.