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Frog-cell ‘neurobots’ grow self-organized nervous systems and alter gene activity

Biobots, whose growing line of variants started with xenobots, are fascinating tiny self-powered living robots built exclusively using frog embryonic cells. Originally developed in the laboratories of Wyss Institute Associate Faculty member and Tufts University Professor Michael Levin, Ph.D. and his collaborators at University of Vermont, biobots are remarkably motile, moving autonomously through aqueous environments.

Since then, the team has shed light on many exciting properties of biobots, including their ability for kinematic self-replication, and responding to sound stimuli.

Biobots can similarly be constructed using human cells in the form of anthrobots, which have the ability to heal neural wounds in vitro. Thus, a vision emerged that biobots, made out of patients’ own cells, could one day be deployed to repair spinal cord or retinal nerve damage, clear plaques from the arteries, locally deliver pro-regenerative drugs, and perform other vital tasks in the human body.

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