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A Phase 1 Dose-Escalation Trial of Reirradiation for Patients With Recurrent Glioblastoma

New in practicalRO: radonc.


A dose-escalation trial of reirradiation (reRT) was conducted in patients with a diagnosis of recurrent glioblastoma (rGBM) to increase the total overall dose given to the tumor without increasing toxicity. The primary objective of this study was to establish the maximum tolerated dose (MTD) for reRT in patients with rGBM.

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