In this Research Article, Denis Comte & team link defective mitochondrial recycling to impaired natural killer cell function in SLE and identify potential treatments to restore immune balance:
The image shows transmission electron microscopy of an NK cell from a patient with lupus showing mitochondrial structural alterations (false-colored red). Inset: healthy NK cell with preserved mitochondrial ultrastructure.
1Department of Medicine, Division of Immunology and Allergy, Lausanne University Hospital, University of Lausanne, Lausanne, Switzerland.
2Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA.
3Department of Immunobiology, University of Lausanne, Epalinges, Switzerland.