Intraductal papillary mucinous neoplasm and pancreatic cancer: opportunity knocks twice hamada, et al.

📕 doi.org/10.14309/ajg.

L, the wide variation in cancer risk necessitates prolonged surveillance for most patients. There is an unmet need to optimize surveillance strategies for patients with IPMNs to address the rising global mortality associated with pancreatic cancer and to balance early cancer detection against healthcare resource allocation. While published guidelines outline common risk factors of carcinoma derived from IPMN, the resource-intensive nature of surveillance underscores the need for more granular management strategies—a need not yet reflected in current recommendations. Moreover, it is important to appreciate that patients with IPMNs also face an elevated risk of developing pancreatic carcinoma arising concomitantly with IPMN. This type of carcinoma presents unique challenges for surveillance but also offers novel opportunities for the timely identification of incident pancreatic cancer.