Sunny Y. Wong & team characterize gene expression changes that occur during acne pathogenesis and identify a therapeutic that reduces acne-like pustule formation in a mouse model of high fat diet-induced folliculitis:

The image shows prominent neutrophilic pustules from ear skin of the mouse model, stained for the neutrophil marker Ly6G (green) and KRT14 (red).

Address correspondence to: Sunny Y. Wong or Joseph S. Durgin, Department of Dermatology, University of Michigan, 1,500 E. Medical Center Dr., Ann Arbor, Michigan 48,109, USA. Email: [email protected] (SYW); [email protected] (JSD).