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The fetal trophoblast cell marker HLA-G activates a type I interferon response in primary NK cells through the receptor KIR2DL4

Scientists have discovered how cells from the fetus could activate maternal natural killer cells during early pregnancy, helping to demystify the poorly understood mechanisms that govern immune cells at the maternal-fetal interface.

Learn more in Science Signaling.


A fetal cell antigen interacts with a natural killer cell receptor to induce antiviral gene expression.

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