Research Letter: CAR T cells targeting the glycoprotein GD2 show potent antitumor efficacy in high-risk ependymoma models.

Antonio Carlos Tallon-Cobos & team establish a new ependymoma model for preclinical research and demonstrate a promising immunotherapeutic approach for this largely aggressive pediatric brain cancer.

¹Princess Máxima Center for pediatric oncology, Utrecht, Netherlands.

²Hopp Children’s Cancer Center Heidelberg (KiTZ), Heidelberg, Germany.

³Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ) and German Consortium (DKTK), Heidelberg, Germany.