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New understanding of how red blood cells are created could make artificial blood easier to make

A breakthrough in the understanding of how mammals create red blood cells by Dr Julia Gutjahr, who began her research into the mechanisms of blood production in the lab of Professor Antal Rot in the Faculty of Medicine and Dentistry, could lead to opportunities for articifical blood to be created at scale for the first time.

Dr Gutjahr is now a biologist at the Institute of Cellular Biology and Immunology Thurgau at the University of Konstanz in Germany. She identified the molecular signal, chemokine CXCL12, that triggers the expulsion of the nucleus by the red blood cell precursors, a key step in the development of red blood cells.


Studies undertaken by researchers at Queen Mary and University of Konstanz have identified a critical chemical signal in the development of red blood cells. The discovery will help make the manufacture of artificial blood more efficient.

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