Paolo Fiorina & team show TMEM219 blockade re-establishes intestinal self-renewal properties in inflammatory bowel disease:

The figure shows colon samples of naive mice, mice receiving T cells plus PBS, and mice receiving T cells plus anti-p40 or ecto-TMEM219.

¹International Center for T1D, Pediatric Clinical Research Center Romeo ed Enrica Invernizzi, Department of Biomedical and Clinical Sciences, Università degli Studi di Milano, Milan, Italy.

²Division of Endocrinology, ASST Fatebenefratelli-Sacco, Milan, Italy.

³Enthera, Milan, Italy.