Summary: Scientists have used advanced X-ray phase-contrast tomography (XPCT) to uncover how gut health may influence Alzheimer’s disease. The study found structural changes in the gut of Alzheimer’s-affected mice, revealing abnormalities in intestinal cells, neurons, and mucus secretion.

This supports the hypothesis that harmful gut bacteria may escape into circulation, triggering brain inflammation and neurodegeneration. The findings highlight the gut-brain connection and provide a new tool for detecting early disease markers.

Researchers aim to further explore how the enteric nervous system communicates with the brain in Alzheimer’s. The study paves the way for potential new therapeutic targets based on gut health.