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Introducing GPT-6 Astra: the most intelligent and aligned model in the world

GPT-6 Astra achieves state-of-the-art results on benchmarks for long-running computer-use tasks across professions and desktop apps, which means anything you can do on a computer, Astra can do for you, fast.

It’s also the best model for software engineering to date and our most aligned model yet, with improvements in honesty and reductions in deceptive behavior.

GPT-6 Astra is rolling out today for enterprises and customers in our Trusted Access Program, with broad availability in ChatGPT Work and Codex coming to Plus, Pro, Business and Enterprise plans, and API and AWS customers in the next few days.

To experience Astra at its best, use the ChatGPT desktop app.

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The brain-changing benefits of exercise

What’s the most transformative thing that you can do for your brain today? Exercise! says neuroscientist Wendy Suzuki. Get inspired to go to the gym as Suzuki discusses the science of how working out boosts your mood and memory — and protects your brain against neurodegenerative diseases like Alzheimer’s.

How Jeff Bezos Started Amazon #jeffbezos #amazon #successstory

In this rare 1997 interview, a young Jeff Bezos explains the brilliant, mathematical logic behind the founding of Amazon.com. After seeing that web usage was growing at 2,300% a year, Bezos systematically made a list of 20 products to sell online. He chose books because there were over 3 million active titles in print—a volume of inventory that allowed him to build an online store that simply couldn’t exist in the physical world. Jeff Bezos is the founder and executive chairman of Amazon, and one of the most successful entrepreneurs in modern history. #Entrepreneurship #Success #Business #Startup #Mindset #JeffBezos #Amazon #TechHistory …

Scientists Can Now See DNA Folding at Near-Molecular Resolution

The finding could eventually enable the use of DNA packaging in cells for disease diagnosis and treatment.

In preserved cells, newly developed fluorescent probes allowed researchers to pinpoint individual dye molecules to within 3 nanometers, close to the width of the DNA double helix itself. The same molecules can also reveal how DNA is packaged and moves inside living cells, giving scientists a way to examine chromatin at resolutions that were previously difficult to achieve without killing the cells.

When the team tested the probes on wax-preserved bowel tissue from three cancer patients, they found another striking difference. DNA in the tumors appeared noticeably looser and more spread out than in healthy tissue immediately beside it. Other research has found that DNA progressively unpacks as cancer develops, raising the possibility that its degree of folding could eventually provide information about how advanced or aggressive a tumor is.

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