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Engineers at the UCLA Samueli School of Engineering have introduced a universal framework for point spread function (PSF) engineering, enabling the synthesis of arbitrary, spatially varying 3D PSFs using diffractive optical processors. The research is published in the journal Light: Science & Applications.

This framework allows for advanced imaging capabilities—such as snapshot 3D —without the need for spectral filters, axial scanning, or digital reconstruction.

PSF engineering plays a significant role in modern microscopy, spectroscopy and computational imaging. Conventional techniques typically employ phase masks at the pupil plane, which constrain the complexity and mathematical representation of the achievable PSF structures.

Dr. Mohammed Enayat has access to all sorts of experimental antiaging treatments at his clinic, but a core part of his longevity routine is pretty cheap and accessible: supplements.

Enayat told Business Insider that his most recent “biological age” tests, taken 18 months ago, said he was 24, or 17 years younger than his chronological age of 41. There’s no consensus on how to define or measure biological age, but Enayat used GlycanAge and TruAge PACE, which measure inflammation and epigenetics, respectively.

The primary care doctor, who’s also the founder of London’s Hum2n longevity clinic, has been closely tracking his health for the past seven years, using wearable tech, including an Oura ring and a Whoop strap, plus regular blood, urine, and microbiome tests.

Researchers led by Kenichiro Itami at the RIKEN Pioneering Research Institute (PRI) / RIKEN Center for Sustainable Resource Science (CSRS) have successfully used insects as mini molecule-making factories, marking a breakthrough in chemical engineering. Referred to as “in-insect synthesis,” this technique offers a new way to create and modify complex molecules, which will generate new opportunities for the discovery, development, and application of non-natural molecules, such as nanocarbons.

Molecular nanocarbons are super tiny structures made entirely of carbon atoms. Despite their minuscule size, they can be mechanically strong, conduct electricity, and even emit fluorescent light. These properties make them ideal for use in applications like aerospace components, lightweight batteries, and advanced electronics. However, the precision required to manufacture these tiny structures remains a major obstacle to their widespread use. Conventional laboratory techniques struggle with the fine manipulation needed to put these complex molecules together atom by atom, and their defined shapes make it especially difficult to modify them without disrupting their integrity.

“Our team has been conducting research on molecular nanocarbons, but along with that, we’ve also developed molecules that act on mammals and plants,” says Itami. “Through those experiences, we suddenly wondered — what would happen if we fed nanocarbons to insects?”

As neuro-ophthalmology educators, we have sought ways to improve the teaching of pupil-related disorder, focusing on incorporating their dynamic aspects and active learning. Our solution is an app for smartphone and tablet devices. The app, Pupil Wizard, provides a digital textbook featuring a dynamic presentation of the key pupillary abnormalities. It allows the users to interact with a digital patient and explore how each condition responds to direct and indirect light stimuli, near focus, and changes in ambient light (Fig. 1). Moreover, the users can test their knowledge in quiz mode, where random pupillary abnormalities must be correctly identified and multiple-choice questions about them answered.


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Scientists have made liquid carbon in a lab for the first time, Interesting Engineering reported.

Liquid carbon was thought to be impossible to study under normal conditions. The material only exists for billionths of a second under extreme pressure and temperatures of about 4,500 degrees Celsius, making this record-breaking technology limitless in its potential.

Nuclear fusion, combining light atomic nuclei to release massive amounts of clean energy, has long been considered the holy grail of power generation. Fusion could change society by providing unlimited electricity without radioactive waste, helping cities, individuals, and companies save money compared to resource-intensive traditional energy methods.

A series of studies sheds light on the origins and characteristics of intermediate-mass black holes. In the world of black holes, there are generally three size categories: stellar-mass black holes (about five to 50 times the mass of the sun), supermassive black holes (millions to billions of times the mass of the sun), and intermediate-mass black holes with masses somewhere in between.

While we know that intermediate-mass black holes should exist, little is known about their origins or characteristics – they are considered the rare “missing links” in black hole evolution.

However, four new studies have shed new light on the mystery. The research was led by a team in the lab of Assistant Professor of Physics and Astronomy Karan Jani, who also serves as the founding director of the Vanderbilt Lunar Labs Initiative. The work was funded by the National Science Foundation and the Vanderbilt Office of the Vice Provost for Research and Innovation.

ChatGPT-maker OpenAI has enlisted the legendary designer behind the iPhone to create an irresistible gadget for using generative artificial intelligence (AI).

The ability to engage digital assistants as easily as speaking with friends is being built into eyewear, speakers, computers and smartphones, but some argue that the Age of AI calls for a transformational new gizmo.

“The products that we’re using to deliver and connect us to unimaginable technology are decades old,” former Apple chief design officer Jony Ive said when his alliance with OpenAI was announced.

The University of California San Diego is part of a new research partnership led by San Diego-based General Atomics that was recently awarded funding by the U.S. Department of Energy (DOE). The project, called the Target Injector Nexus for Experimental Development (TINEX), aims to overcome critical obstacles in developing and scaling up inertial fusion power plants.

It is one of six awards, collectively totalling $107 million, made by the DOE as part of the Fusion Innovative Research Engine (FIRE) Collaboratives.

“The TINEX project will be important for our collective efforts to make inertial fusion energy practical,” said mechanical engineering professor Javier E. Garay, director of the Fusion Engineering Institute at the UC San Diego Jacobs School of Engineering.