In IDB, macrophages, a type of immune cell begins producing excessive levels of pro-inflammatory cytokines. These proteins then stick to macrophage receptors which triggers them to produce even more of this inflammatory protein. But UC San Diego researchers can break that cycle with a microrobot.
In previous experiments, UC San Diego researchers delivered drugs with microrobots, most notably in the lungs, and succeeded in minimizing the drug’s side effects. For the IBD study, however, they didn’t even need to use a drug.